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Postdoctoral Research Scientist - Organelle Dysfunction in Neurodegenerative Disease

University of Oxford - Nuffield Department of Medicine

Location: Oxford
Salary: £32,817 to £40,322 32,817 - £40,322 per annum, Grade 7 (with a discretionary range from £41,526 - £44,045 per annum)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 7th April 2021
Closes: 5th May 2021
Job Ref: 150528

Nuffield Department of Medicine, Target Discovery Institute, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ

Grade 7: £32,817 - £40,322 per annum (with a discretionary range from £41,526 - £44,045 per annum)

We are seeking to appoint a postdoctoral scientist to build a newly formed Organelle Biology team within the Alzheimer’s Research UK Oxford Drug Discovery Institute (ARUK-ODDI), in the Nuffield Department of medicine, University of Oxford. Applicants will have a passion for research into the mechanisms underlying neurodegenerative diseases, particularly Alzheimer’s disease and Parkinson’s disease. This is a key post, reporting to the Organelle Biology team leader (Dr Margarida Ruas), and will be critical to the direction and success of the team. You will be a member of a research team and conduct research into the dysfunction in organelle and subcellular trafficking that occurs in neurodegenerative diseases. The post-holder will be a skilled molecular & cellular biologist with experience in neurobiology, responsible for designing and executing experimental plans in order to complete the objectives of the team. You will be responsible for proposing and developing discrete areas of project work within the ODDI’s portfolio.

You must hold a relevant PhD/DPhil in Biology or related, with post-qualification research experience relevant to the field of subcellular organelles or trafficking. You will have sufficient specialist knowledge to develop research projects and methodologies relevant to the field, including, for example: neuronal cell culture, ideally of iPSC-derived neuronal cultures, manipulation of iPSCs by CRISPR, and measurement of cellular phenotypes using high-content imaging. Your primary role will be to conduct laboratory research and champion the science in support of specific targets, however, in addition, you will need to supervise the laboratory work of students or RAs, taking responsibility for their training and health and safety, and you will also take responsibility for key pieces of technology.

This full-time position is fixed-term for three years in the first instance and is funded by the Alzheimer’s Research UK.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

Only applications received before 12.00, midday on 5 May 2021 can be considered. Please quote reference, 150528 on all correspondence.

Closing Date: 05-MAY-2021 12:00

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