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Research Fellow/Senior Research Fellow (Software Engineering)

UCL - Sainsbury Wellcome Centre

The appointment will be on UCL Grade 7-8

The Sainsbury Wellcome Centre (SWC) commenced research operations in Spring 2016 bringing together world-leading scientists to investigate how brain circuits process information to generate perception, form memories and guide behaviour. Developed through the vision and partnership of the Gatsby Charitable Foundation and Wellcome, and with substantial investment from these partners, the mission of the SWC is to generate experimentally testable theories of brain function.

The Margrie lab is focused on studying cell-to-cell diversity within and across different neuronal classes and networks, in the context of local and long-range connectivity. It is their view that only a detailed quantitative understanding of the heterogeneity in connectivity and cellular composition of the network can elucidate key principles underlying the design and operation of neuronal circuits in the normal and diseased brain.

From a technical standpoint, the lab employs a variety of approaches, some of which are multidisciplinary and/or were developed in the Margrie lab. These include 3D electron microscopic analysis, in vitro and in vivo single and multi-cell targeted recordings, whole-brain connectivity mapping of recorded cells, optogenetics, modelling, and behaviour.

The Margrie lab is focused on dissecting brain function at the cellular level using two model systems. The primary visual cortex is perhaps the most studied cortical area. At a functional level it is highly plastic and contains functionally and biophysically diverse cell types.

The glomerular circuit of the olfactory bulb is another model system of choice, as local networks can readily be identified and genetically targeted from one mouse to the next.  The lab is also committed to the development of novel, open-source data analysis software for the community. The lab recently co-founded the BrainGlobe Initiative to develop interoperable Python-based computational neuroanatomy software.  The Margrie lab is looking for an outstanding postdoctoral researcher or research software engineer to be responsible for creating, maintaining and supporting data analysis software. This is an exciting opportunity to work in a highly collaborative and multidisciplinary environment which will include the training of team members.

The post is funded until 31 October 2025 in the first instance.

You will have a proven track record of developing software to analyse biological data, along with a knowledge of modern systems neuroscience methods. Significant experience in Python programming, digital image processing and biological data analysis is essential. The role requires knowledge and experience of modern software development best practices. Excellent communication and analytical skills are essential.  Candidates wishing to be appointed as a Senior Research Fellow should demonstrate experience of guiding and supervising a small team of researchers and laboratory support staff.

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

If you have any queries regarding the vacancy or the application process, please email the Sainsbury Wellcome Centre HR team,

Latest time for the submission of applications: 23:59.

Interview Date: To be confirmed

We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level.

UCL Taking Action for Equality

Our department is working towards an Athena SWAN award. We are committed to advancing gender equality within our department.

Location: London
Salary: The salary range will be Grade 7 £36,770 - £44,388 per annum or Grade 8 £45,610 - £53,757 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 9th September 2021
Closes: 3rd October 2021
Job Ref: 1879134
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