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Research Associate - Chemist/Chemical Biologist to study DNA base modifications and their epigenetic functions (Fixed Term)

University of Cambridge - Yusuf Hamied Department of Chemistry

Location: Cambridge
Salary: £33,309 to £40,927 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 28th September 2021
Closes: 11th November 2021
Job Ref: MA27502

Salary: £33,309-£40,927

Reference: MA27502

Closing date: 09 November 2021

Fixed-term: The funds for this post are available for 2 years in the first instance.

We seek a postdoctoral scientist to work with Professor Sir Shankar Balasubramanian on a Wellcome Trust- funded programme to investigate the structure and function of chemically modified nucleic acid bases. This is an interdisciplinary project that encompasses the use of biophysics, chemical biology and molecular biology on DNA and on the genome. See DOI: 10.1021/jacs.9b01915, DOI: 10.1038/s41570-017-0069, for further information.

We look to appoint a chemist or chemical biologist to explore how chemically modified DNA bases affect the structure and function of DNA. The research will involve chemistry and enzymology of nucleic acids, protein- DNA interactions, epigenetics, chromatin structure and transcription. We aim to gain a deeper understanding of the function of base modifications and their involvement in regulating gene expression in normal and disease states using cellular models from human, and mouse and also parasite models.

The successful candidate will have a capacity for innovation and creativity. We value good communication skills and the ability to work as part of a multi-disciplinary team.

Candidates should have (or be about to receive) a PhD in a relevant discipline.

The position is available immediately.

To apply online for this vacancy and to view further information about the role, please visit :

Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter that explains your motivations for the position and your publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For queries regarding this post, please contact Jo Lockhart, Science Administrator, Balasubramanian Group, email:

Please quote reference MA27502 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN silver award for women in science, technology, engineering, mathematics and medicine.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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