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Postdoctoral Researcher

University of Dundee - Cell Signalling and Immunology

Location: Dundee
Salary: £33,309 to £40,927 Grade 7.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 9th November 2021
Closes: 9th December 2021
Job Ref: SLSC0974

Job Description
A 6-month Postdoctoral Research Associate position is available with Dr Henry McSorley within the Division of Cell Signalling and Immunology at the University of Dundee, to carry out research on an MRC-funded project on modulation of IL-33 responses by parasite proteins. This is a short-term position due to extension of funding.

This position will involve working on the MRC-funded New Investigator Research Grant entitled “Modulation of IL-33-dependent responses using parasite products”. This project has led to the discovery of a new family of IL-33-suppressing proteins (“HpBARI” Vacca, 2020, eLife) and an IL-33-amplifying protein (“HpARI_CCP1/2” – Chauché, 2020, Frontiers Immunol). We are currently finishing investigations on further IL-33-modulating parasite-derived proteins and plan to submit a manuscript in 2022, once final experiments have been completed. This short-term position will allow completion of these experiments and further investigations on the effect of IL-33 in neutrophilic responses.

Experimental techniques will include parasite infections, protein-protein interaction experiments, in vitro cellular assays and immunological assays (e.g. flow cytometry, qPCR, confocal imaging).

This position is an excellent opportunity to join a dynamic research group, and help to drive an exciting and cutting-edge research programme. The McSorley lab is a friendly and enthusiastic set of research scientists, with expertise in parasitology, immunology and molecular biology. We are looking for a candidate who will bring new skills to the group, and will have the ambition and determination to propel this project onwards and answer the research questions which we in the group are passionate about. You will have access to Dundee’s world-class research environment, which is open, collegiate and friendly, and has excellent facilities for meeting all parts of our research agenda.

Essential Attributes

  • PhD in a relevant field such as Immunology, Infectious Disease, Molecular Biology or Cellular Biology.
  • Experience of immunology, biochemistry or cell biology research.

Desirable Skills

  • Technical expertise in flow cytometry or fluorescent imaging techniques.
  • Experimental design experience and expertise.
  • An ambitious and driven candidate.
  • Proteomic experience.
  • Protein-protein interaction assays.
  • In vivo experimental design and implementation.

Appointment as a Postdoctoral Researcher on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. In this case the initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 25 - 28).

Additional Information:
We are one of the UK’s leading universities – internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others.

The University of Dundee is a signatory of the Researcher Development Concordat and is committed to enhancing the research environment and culture. Engagement and support of activities which assist the researcher development agenda at the University is therefore essential.

For further information about this position please contact hmcsorley001@dundee.ac.uk. To find out more about Cell Signalling and Immunology please visit https://www.lifesci.dundee.ac.uk/research/csi.

As an internationally diverse institution, we welcome job applicants from all countries and nationalities. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well as a full range of disability services, create an enjoyable and inclusive place to work.

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