Postdoctoral Scientist, Translational Oncogenomics Group

Salary in the range: £31,604 - £41,929 (dependent upon qualifications and experience)

3 years fixed term

Ref: MI/22/13_2

About the role:

A 3 year Postdoctoral Scientist position is available in the laboratory of Professor Rob Bristow to investigate the role of DNA damage and genome instability in the progression and treatment of prostate cancer. We are looking for an individual with experience in molecular and cellular biology to join our multidisciplinary team. The post-holder will be involved in the characterization of novel genetic models exploring the relationship between DNA repair deficiency and the development of high-risk prostate cancer.

About you:

You should have a PhD in either oncology, molecular biology or genomics along with relevant laboratory experience in cellular and tumour biology. You should be accustomed to working with human tissue cultures, and experience in the use of primary human cells for organoid and patient-derived xenograft studies would be an advantage.  Experience of using basic molecular biology and protein analysis techniques such as molecular cloning, gene editing and western blotting is essential. Other relevant techniques including analysis of cell proliferation/death, FACS, recombinant virology, confocal microscopy and DNA repair assays would be an advantage. A background in prostate cancer and genomics is desirable but not essential. 

We are looking for an enthusiastic and motivated colleague to join our team who is keen to generate and share new findings in the field of genome instability in cancer. You should be committed to pursuing a career in research and working towards establishing yourself as an independent researcher in oncology. We will consider applications from recently qualified and more experienced post-doctoral scientists.

Why choose Cancer Research UK Manchester Institute?

The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research.  The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK Manchester Institute, Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe.  These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

How to apply?

To apply for this position please visit our website.

For any informal enquiries about this post, please contact Steve Lyons: steve.lyons@cruk.manchester.ac.uk

Closing date: Thursday 30 June 2022

Cancer Research UK Manchester Institute is a Research Institute within The University of Manchester and is core funded by Cancer Research UK

Advert information