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Research Assistant: Hannon lab x 2 (Fixed Term)

University of Cambridge - Cancer Research UK Cambridge Institute

Location: Cambridge
Salary: £27,929 to £32,348
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 5th December 2022
Closes: 2nd January 2023
Job Ref: SW34512

The Hannon laboratory at the CRUK Cambridge Institute (part of the University of Cambridge) is seeking to hire two Research Assistants to join a team of scientists studying the spatial architecture of triple-negative breast cancer (TNBC) and its response to treatment. This role will require interaction with an interdisciplinary team. Greg Hannon is the lead investigator, with co-Principal investigators Jean Abraham and John Marioni and co-investigators Jasmin Fisher, Dario Bressan, Menna Clatworthy, Walid Khaled, and Sam Aparicio.

With support from a CRUK Grand Challenge grant, we have substantial capabilities for carrying out spatial molecular profiling. This expertise resulted in us being awarded funding as part of the Wellcome Leap Delta Tissue Program (https://wellcomeleap.org/delta-tissue/).

As part of the delta tissue program, we are running a project that aims to profile the 'tissue state' of TNBC prior to and after neo-adjuvant chemotherapy in responders and non-responders with the goal of creating a model to predict tissue end state from its initial state.

As part of the Wellcome Leap delta tissue program, we have the fantastic opportunity of hosting the world's largest spatial proteomics laboratory with the aim of pushing the boundaries of what is currently possible within the field.

We are currently looking to recruit 2 Research Assistants to the team whose responsibility it will be to work together to prepare human samples for spatial proteomic analysis (using Image Mass Cytometry) on a huge scale in human TNBC samples. As such, the selected applicant must have existing experience within a reputable molecular biology laboratory and ideally have experience in staining techniques on tissue sections [e.g., image mass cytometry (IMC), immunohistochemistry (IHC) or immunofluorescence (IF)]. Experience working with human tissue is desirable, as are other molecular biology techniques.

The successful candidates should also show initiative and independent thinking, possess excellent communication skills and the ability to work effectively as part of a team. They will also be expected to periodically report results for the funder and/or in lab meetings and project meetings that take place in person or via teleconference.

Applicants should have a B.Sc. or M.Sc. degree in a relevant discipline.

Fixed-term: The funds for this post are available for 20 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

Closing Date: 2nd January 2023

Interview Date: estimated 9th - 13th January 2023

To apply online for this vacancy and to view further information about the role, please visit :

http://www.jobs.cam.ac.uk/job/38517.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference SW34512 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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