Location: | Southampton |
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Salary: | £33,314 to £40,931 Per annum |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 5th January 2023 |
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Closes: | 3rd February 2023 |
Job Ref: | 2119122BJ |
Job description
The Gwyer Findlay lab investigates how neutrophils affect T cell phenotype. Our work sits at the interface of immunology and inflammation biology and we use a variety of methods in our studies – immunology, molecular biology, computational biology and imaging.
In this project we are aiming to understand how neutrophils alter T cell cytokine production. We have previously shown that when neutrophils release antimicrobial peptides, they enter nearby T cells and profoundly alter T cell cytokine production. In particular, they affect the production of the IL-17 family of cytokines. In this project we will work out how this occurs. Through culture of mouse and human T cells, flow cytometry, RNA and ATAC sequencing and imaging, we will examine the signalling pathways induced by neutrophil peptides and how they lead to differential IL-17 production.
You will hold a PhD in immunology, biology, or a related discipline. Highly organised and driven, you will demonstrate initiative and problem-solving skills. You will have experience in and knowledge of T cell immunology, cell culture, and flow cytometry.
Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.
For additional information or informal enquiries before submitting your application, please email Emily Findlay at e.gwyerfindlay@soton.ac.uk.
Application Procedure
You should submit your completed online application form by clicking the 'Apply' button above. The application deadline will be midnight on the closing date stated above. References are requested along with your application. This reference system is automated so please ensure you provide the correct email address and allow time for these to be received, prior to the close date, to assist the department with shortlisting.
If you need any assistance, please call Sian Gale (Recruitment Team) on +44 (0) 23 8059 2750, or email recruitment@soton.ac.uk. Please quote reference 2119122BJ on all correspondence.
Further details:
We believe equality, diversity and inclusion are fundamental to making the University of Southampton a welcoming, vibrant and successful organisation. Having a diverse workforce, inclusive of people of all ages and beliefs, from different racial, educational and social backgrounds opens up a wealth of possibilities, makes us more creative and accelerates our impact on society. We welcome applicants that value the diversity of our community and are willing to play their part in supporting the mission of inclusivity.
Please note that applications from agencies will not be accepted unless indicated in the job advert.
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