Research Associate/Fellow (Fixed Term)

Location: UK Other

Salary: Salary progression beyond this scale is subject to performance

We are looking to recruit an individual with a background in neuroscience and or arthritis, and experience with in vivo models, ideally with an interest in the mechanisms of pain and / or arthritic diseases. This project builds upon our previous funded research investigating the role of the resolution of inflammation in chronic osteoarthritis pain. This project seeks to identify the therapeutic potential of small noncoding RNAs for the treatment of chronic osteoarthritis pain. This project is funded by the Advanced Pain Discovery Platform, which will provide the successful applicant opportunities to engage with the wider pain community across the UK and beyond.  For more information: https://apdp.sixcircles.co/

This post will be embedded within the wider pain research team funded by this project, which includes clinical research, analytical sciences, molecular and cellular neuroscience, RNA biology, transcriptomics, and bioinformatics. In this role, you will use models of osteoarthritis pain and patients’ tissues and fluids to address the aim of this exciting project. Full training will be provided, as required. Experience of in vivo methods in rodents, including the generation of rodent models of human disease and the assessment of behavioural changes will be ideally matched to this research project. An interest in, or desire to learn, transcriptomics and bioinformatic analysis and the forward and back-translation of datasets will be welcomed, as will an interest in working in collaboration with cellular biologists on the implementation of in vitro models of neuronal sensitisation. We hope to recruit somebody who brings new skills to our project to strengthen our research team and provide new opportunities for novel ways of thinking. The successful candidate will work closely with Eli Lilly, providing exposure, to and benefit from, the pharmaceutical sector.

The Pain Centre Versus Arthritis at the University of Nottingham provides a vibrant environment for pain and neuroscience research, facilitating forward and back-translational studies investigating the mechanisms of osteoarthritis pain with the goal of improving the treatment of pain (see: http://www.nottingham.ac.uk/paincentre).  

Candidates must hold, be near to completion of, or studying towards a PhD or equivalent in an appropriate subject (e.g. pharmacology, neuroscience, physiology, biochemistry). Candidates should have a strong background in neuroscience research with a focus on animal models of human disease, ideally including knowledge of pain processing and mechanisms of chronic pain or arthritic disease.  Experience of transcriptomics and a desire to build upon pre-existing skillsets is encouraged.

This is a full-time (36.25 hours), fixed-term post for 2 years. Job share arrangements may be considered.

Informal enquiries may be addressed to victoria.chapman@nottingham.ac.uk. Please note that applications sent directly to this email address will not be accepted.

Our University is a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. For more information on the support we offer our international colleagues, see our Moving to Nottingham pages.

For successful international applicants, we provide financial support for your visa and the immigration health surcharge, plus an interest-free loan to help cover the cost of immigration-related expenses for any dependants accompanying you to the UK. For more information see Financial support for visas and the immigration health surcharge.

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