|Salary:||The starting salary will be from £39,745 on Grade F, depending on qualifications and experience.|
|Placed On:||3rd February 2023|
|Closes:||16th February 2023|
The University of Exeter Medical School wishes to recruit a Postdoctoral Research Fellow to participate in an exciting new collaborative translational genomics initiative (PARADIGM). This 5-year Wellcome-funded post is available from 1 March 2023. The successful applicant will work on gene expression in fetal brains using long-read sequencing technologies, and investigate the importance of novel RNA isoforms to severe monogenic developmental disorders. The individual will be a member of several research teams at the University of Exeter (led by Professors Caroline Wright and Jon Mill) as well as being part of a wider collaborative network of genomics researchers across the UK.
About the project
Despite progress in genome sequencing, the majority of patients affected by rare diseases remain undiagnosed. The PARADIGM initiative will tackle this problem by creating new Primary Annotated Resources to Advance Discovery In Genomic Medicine. PARADIGM is a collaboration between researchers at the Universities of Exeter, Edinburgh, Imperial, and Cambridge as well as the European Bioinformatics Institute (EMBL-EBI) and Wellcome Sanger Institute. By combining machine learning approaches with high-resolution functional data and genome sequences from patients (including the Deciphering Developmental Disorders Study and 100,000 genomes project), we aim to find novel genetic causes of monogenic disease. This post forms a core part of PARADIGM, and will include:
Applicants will possess a relevant PhD or equivalent qualification/experience in a related field of study. The successful applicant will be able to develop research objectives, analyse large datasets, draft research manuscripts, make presentations at conferences, and contribute to the process of securing funding. Experience analysing large genomic datasets and an understanding of genomic medicine is desirable. The successful applicant will be able to work collaboratively and willing to help supervise others.
Please ensure you read the Job Description and Person Specification for full details of this role by clicking on the attachment.
What the University of Exeter can offer you
Exeter is a member of the prestigious Russell Group of research-intensive universities and in the top 150 universities in the world (Times Higher Education World University Rankings 2022 and QS World University Ranking 2022). We combine world-class teaching with world-class research, with over 27,000 students and 6,400 staff from 180 different countries. We are committed to an inclusive culture where all members of our community are supported to thrive. We offer:
For further information please contact Caroline Wright (firstname.lastname@example.org).
The closing date for completed applications is 09/02/2023. Interviews are expected to take place around early March.
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