Research Associate- In bacterial membrane proteomics (Fixed Term)

Postdoctoral researcher to apply proteomics technologies to an ancient universal bacterial membrane effector system

The post is a key part of a major 5-year BBSRC sLoLa award to understand an ancient universal membrane effector system, and tackle outstanding question of how members of the microbial IM30 protein family function to protect biological membranes from different stresses and stop dissipation of electrochemical gradients. Our understanding of this fundamental and ancient system underpins many areas of research including industrial biotechnology, antimicrobial resistance and virulence of human pathogens.

The project is a collaboration involving multidisciplinary teams: Universities of York (Gavin Thomas, Jamie Blaza, Luke Mackinder, Ben Willson), Cambridge (Kathryn Lilley), Nottingham (Boyan Bonev), Newcastle (Henrik Strahl), Mainz (Susanne Gebhard)

We are seeking to employ a post-doctoral research associate (PDRA) based in the laboratory of Prof. Kathryn Lilley, Cambridge Centre for Proteomics (CCP), University of Cambridge. This PDRA will be involved in quantitative proteomics measurements, interrogation of the phosphorylation status of IM30 family membranes, and interactions of these proteins using proximity labelling and application of SMALP technology (doi: 10.7554/eLife.74322).

CCP is equipped with cutting-edge mass spectrometry equipment and its research focus is the development and application of methodologies at the interface of cell biology and proteomics'

We particularly encourage candidates to apply who have a strong background in membrane proteomics, subcellular fractionation, and mass spectrometry. Experience with the application of proteomics informatics tools is also desirable.

Fixed-term: The funds for this post are available for 48 months in the first instance.

For informal enquiries can be sent to Professor Lilley: k.s.lilley@bioc.cam.ac.uk

For any questions about this vacancy or the application process please contact: personnel@bioc.cam.ac.uk

Please quote reference PH35886 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Advert information