Research Associate in Flow Cytometric Preparation and Analysis of Mitotic Chromosomes

Location: South Parks Road, Oxford              

We are seeking to appoint a Research Associate to join the research group of Prof Amanda Fisher to support an interdisciplinary team working at the intersection between chromosome biology, flow cytometry, microfluidics and molecular/epigenetic analysis. The group’s current work focuses on determining the repertoire and role of proteins that remain bound to mitotic chromosomes through cell division. This uses molecular, genetic and biochemical approaches to disrupt and/or degrade mitotic proteins and evaluate the relevance of such factors in determining chromosome structure and the transmission of cellular identity. To do this we develop new ways of isolating and manipulating native mitotic chromosomes from different organisms using flow cytometry and microfluidic approaches, and then interrogate the function of proteins postulated to ‘bookmark’ the genome through mitosis. We are looking for a dedicated individual to lead the development of technology in this area, supported by existing close collaborations with staff at the MRC LMS. 

Applicants should hold a BSc or MSc degree in a relevant subject area related to Biology, biotechnology or biophysics and possess sufficient specialist knowledge to work within the established research programme. You will have knowledge and experience in molecular, cellular or chromosome biology and have the capacity to learn and develop skills in cytometry and have a rigorous approach to data collection and reproducibility. Experimental and analysis skills are essential as is having the capacity to communicate with others and conveying information in a clear and concise manner. You will have excellent verbal and written communication skills and have the ability to work as part of a team and individually. 

This full time fixed-term post is funded by the MRC for up to 3 years in the first in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford. 

This position is graded on the University’s grade 7 scale, for which the salary range is £35,308 - £43,155 per annum. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available. 

To apply for this role and for further details including the job description and selection criteria, please see the document below. You will be required to upload a supporting statement and CV as part of your application. 

The closing date for applications is 12.00 noon on Friday 21st April 2023 with interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity.

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