Location: | London |
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Salary: | £51,017 per annum (plus £2,162 London allowance per annum) |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 24th March 2023 |
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Closes: | 17th April 2023 |
Job Ref: | MED03779 |
Location: South Kensington Campus
Job Summary
This post offers a unique opportunity to develop and deliver a first in human study of a novel fluorescent BCG strain designed by Imperial College investigators to help accelerate the development of new vaccines and treatment for tuberculosis.
Tuberculosis remains a global problem with around 1.5 million deaths and 9 million new cases annually, despite the availability of not only a vaccine (BCG) for nearly 100 years, but also effective chemotherapy for over half a century. BCG works least well in endemic areas and antimycobacterial chemotherapy involved multiple drugs over an extended period and antimicrobial resistance has led to extended complex regimens. Experimental medicine in humans has a long history in infectious disease and the current project is develop a human challenge model for tuberculosis to facilitate early-stage screening of novel vaccine, to allow their prioritisation before expensive large scale clinical trials.
We are aiming to recruit an enthusiastic and motivated physician with an interest in infectious disease, academic medicine, and who wishes to expand their research portfolio. The post holder will have an integral role in the set-up and delivery of a new human challenge trial, with responsibility for protocol development, participant recruitment and screening, and clinical care of study participants during and after challenge. The successful applicant will have the opportunity to develop laboratory skills in microbiology and immunology, focussing on challenge strain characterisation and the development of new serological assays. There will also be opportunities to support delivery of other clinical studies (including trials) within the Infection and AMR theme of the Imperial College Biomedical Research Centre.
Duties and responsibilities
Essential requirements
Further Information
This is a Full Time and Fixed Term post for 3 years based in the South Kensington Campus but will require work at clinical partner sites (St Mary’s, Hammersmith and Chelsea and Westminster Campuses) and the Francis Crick Institute as and when required.
Salary upon appointment will also include an additional London Weighting Allowance of £2,162 per annum.
Should you require any further details on the role please contact: Dr Brian Robertson at b.robertson@imperial.ac.uk or Prof Graham Cooke at g.cooke@imperial.ac.uk
Closing date: 17/04/2023
To apply, visit www.imperial.ac.uk/jobs and search by the job reference MED03779.
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