GMP Production/QC Scientist (Stem Cells)

Location: Guy's Campus

Contact details: Professor Rachael Pearson. Rachael.pearson@kcl.ac.uk

Job description

Background

The Ocular Cell and Gene Therapy group, based in KCL’s Centre of Gene Therapy and Regenerative Medicine, develops a wide variety of novel cell and gene therapies for the treatment of neurodegenerative diseases, with a particular emphasis on retinal disease.

This is an exciting opportunity to work at the interface of basic and clinical research in a group that is at the forefront of translating ocular research into clinical application. Led by Professors Robin Ali and Rachael Pearson (previously at UCL’s Institute of Ophthalmology), it is one of the largest cellular and gene therapy groups in the country. Over the past 20 years, the group has led first-in-human clinical trials of gene and cell therapy for eye disease, and we are now in the pre-clinical development phase for clinical trials for photoreceptor cell therapy.  

Role Purpose

The post holder will:

• Work with the pre-clinical team to support the product development, manufacturing and QC testing of GMP grade stem cell-derived ATMPs.  
• Play an active role in aseptic cell manufacturing processes and acquiring and analysing QC data.  
• Assist with quality and document control plus other activities related to maintaining compliance with GMP. 

We are looking for a highly motivated individual who has a demonstrable interest in working with stem cells and developing GMP-compliant manufacturing protocols. This is a unique opportunity to work in a vibrant, collaborative translational research environment with very high potential to learn new skills. 

This post will be offered on a fixed-term contract for 24 months in the first instance.

This is a full-time post - 100% full time equivalent

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