Research Fellow

About us

The UCL Great Ormond Street Institute of Child Health (GOS ICH) The mission of the UCL GOS Institute of Child Health is to improve the health and well-being of children, and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-cla! ss educat ion and training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.

About the role

This is an excellent opportunity to work on a newly funded UKRI Medical Research Council (MRC) project. The successful applicant will be working as part of a newly set up group led by Dr Naresh Hanchate, who is a UCL Excellence Fellow and the holder of the MRC Neuroscience and Mental Health New Investigator Award. The aim of the Hanchate group is to investigate the impact of early life adversities on the brain circuitry, in particular, those that control physiological stress responses. The group employs newly developed genomic technologies (Connect-seq, Nuc-connect-seq) to profile single-cell transcriptomes of individual neural circuit components to understand the impacts of early life adver! sities. T he postholder will perform murine studies, including maintenance of transgenic lines, behavioral and physiological studies, surgical manipulations for stereotaxic delivery of viruses intracranially, preparation of single-cell cDNA libraries, sequencing, and analyses or arrange work with UCL Genomics, supervision of undergraduate and graduate students. The post is funded for 24 months in the first instance and the salary range for this post is £40,524 – £42,705 per annum.

About you

The postholder will have PhD in a relevant field, BSc in Biological sciences, Experience in molecular biology techniques eg cloning, RNAseq, transfection, cellular work, RNASeq. Experience working with viruses at respective biosafety levels, experience performing stereotaxic injections for intracranial delivery of viruses, and experience with mouse neurobehavioral and neuroendocrine analyses are desirable.

What we offer:

Visit https://www.ucl.ac.uk/work-at-! ucl/rewar d-and-benefits to find out more.

Our commitment to Equality, Diversity and Inclusion

At GOS ICH we aim to always have a balanced interview panel that is representative of gender and ethnic diversity. We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level. UCL Taking Action for Equality If you have any queries regarding the application process, please contact Madhur Sharma on quoting job reference B02-05776 

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