Post-Doctoral Research Assistant - UOD996

We are recruiting for an exceptional individual to join our Team, to drive forward an exciting new translational science project characterising the response of the gastrointestinal epithelial barrier to bile acid stimulation, using human tissue derived organoid models and proteomic analysis. This is a fixed-term appointment for 30 months.

Bile acid diarrhoea is a common debilitating disorder, affecting 1 in 100 people in the UK. There is no cure, and it is a lifelong condition. Therefore, there is a clinical need to develop new biomarkers to aid diagnosis and to identify new treatment targets. This project, funded by the Chief Scientist Office in Scotland, is in collaboration with Professor Simon Arthur, School of Life sciences, University of Dundee (Professor Simon Arthur | University of Dundee) who is expert in cell proteomic analysis and Prof Julian Walters, Professor of Gastroenterology at Imperial College, London (Home - Professor Julian Walters (imperial.ac.uk) who is expert in the field of bile acid biology.

This opportunity to join the laboratory based gastrointestinal research program led by Dr McLean, within the wider gastroenterology and hepatology research group, will provide experience and skills in a wide array of laboratory methodologies including organoid culture, proteomics, molecular methods, and data analysis. There will be opportunity to supervise undergraduate/MSc students on placement within the lab team.

Your priorities will include:

• To perform high quality lab-based research within an exciting translational science project.
• Demonstrate excellent communication and organisational skills to drive the project forward.
• Actively contribute to group and divisional meetings, present data at national meetings and take a lead role in manuscript preparation.
• Supervision of undergraduate/MSc students who may have lab-based projects with the team.

Who we’re looking for:

• A candidate with a PhD in cell biology or related discipline.
• Experience of running a project that has demonstrated scientific problem solving and initiative.
• Experience and skills in cell culture and molecular methods. Experience in working with primary cells and/or proteomics is desirable.
• A candidate who demonstrates ability to work independently, and with the rest of the team.
• A candidate who is highly motivated and ambitious with a passion for science.

The University of Dundee is a signatory of the Researcher Development Concordat and is committed to enhancing the research environment and culture. Engagement and support of activities which assist the researcher development agenda at the University is therefore essential.

To find out more about Group, Division & School please visit Dr Mairi McLean | University of Dundee / Division of Molecular and Clinical Medicine | University of Dundee/ School of Medicine | University of Dundee

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

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