Back to search results

Research Associate

King's College London - Faculty of Life Sciences & Medicine - Randall Cell & Molecular Biophysics

Location: London
Salary: £42,405 per annum, including London Weighting Allowance*
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 20th November 2023
Closes: 4th January 2024
Job Ref: 078445
 

Job Description

Applications are invited for two postdoctoral research associate positions in Dr. Angika Basant’s group at the Randall Centre for Cell and Molecular Biophysics, King’s College London.

The Basant group, funded by a grant from the Wellcome Trust, seeks to understand how tyrosine phosphatases regulate cell signalling. This large family of enzymes has been highly understudied compared to its kinase counterpart. We investigate these phosphatases in the context of signalling to the actin cytoskeleton and in virus-infected cells.

Post 1 of 2: The researcher appointed to Post A will focus on candidate phosphatases that have been validated to regulate actin dynamics during infection with the poxvirus Vaccinia. How do these phosphatases function, what are their key interactors and how do they recognise substrates? The broader goal is to contextualise these findings in uninfected cells and, with the help of a collaborator, in other viral infections. For this role, experience in phosphatase biology, cell signalling or biochemistry is desirable but not mandatory.

Post 2 of 2: The researcher appointed to Post B will use quantitative microscopy techniques to elucidate how candidate phosphatases impact phosphotyrosine signalling dynamics and outputs. They will take advantage of, and further develop, a Vaccinia virus-based signalling platform, as well as cutting-edge molecule counting and optogenetics tools available in the lab. For this role, experience in phosphatase biology or cell signalling is desirable but not mandatory.

A PhD in a relevant discipline is required (or applicant to be near completion). A high-quality publication record and effective science communication skills are essential. International applicants are welcome.

Please reach out to Dr. Angika Basant ( angika.basant@kcl.ac.uk) for informal discussions on either posts.

This post will be offered on a fixed-term contract until 30th April 2027.

This is a full-time post. We are looking for candidates to start no earlier than 1st May 2024.

Skills, knowledge, and experience

Essential criteria

  • PhD in a relevant discipline (or close to PhD award)
  • Strong track record in a key subject area such as cell signalling, cytoskeleton or similar
  • Excellent experimental skills and strong ability to lead project design and management
  • An enthusiasm for the research questions being addressed in the lab
  • Strong communication skills both in writing and for oral presentation
  • Collegiality and ability to work well in a research team
  • Ability to work independently, take initiative, learn new skills and troubleshoot technical problems
  • Good time management and organisational skills
  • Scientific rigor and integrity
  • Good practice in health and safety procedures
  • Experience in microscopy (Post B only)

Desirable criteria

  • Experience in supervision and teaching of other researchers
  • Knowledge of phosphatase biology and/or phosphotyrosine signaling
  •  Experience in biochemistry and/or proteomics (Post A only)

* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from King's College London

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge