Back to search results

Research Associate Experimentalist (Gottgens Lab)

University of Cambridge

Location: Cambridge
Salary: £36,024 to £44,263 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 28th November 2023
Closes: 14th January 2024
Job Ref: RB39594

Applications are invited for the position of Research Associate to join the group of Professor Bertie Gottgens within The Wellcome Trust ¿ Medical Research Council Cambridge Stem Cell Institute and Department of Haematology on the Cambridge Biomedical Campus.

The successful candidates will join a collaborative research team, with the aim to identify the molecular changes that give rise to altered leukaemogenic differentiation landscapes in preleukaemic mouse models. This project will take advantage of state-of-the-art single-cell molecular techniques, genetic perturbations and computational analysis to identify and validate previously unrecognized genes/pathways driving aberrant cell fate decisions in pre-leukemic cells. Experiments will include single cell RNA-seq analysis, perturbation of transcription factors using CRISPR-Cas9, testing of therapeutic compounds, mammalian cell culture, in vitro differentiation assays and in vivo models of leukaemia.

Appointment at Research Associate level is dependent on having a PhD, or an equivalent research doctorate in a relevant subject. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once PhD has been awarded.

The post holder will be expected to participate in the design and planning of experiments. They will be required to perform laboratory-based research and engage effectively with bioinformatic and other project collaborators. The ability to learn quickly and to work both independently and as part of a team is essential. The post-holder will become a valued member of the Gottgens Group and will work alongside students and researchers (both wet and dry). Prior experience of haematopoiesis and leukaemia research, single-cell technologies (such as but not limited to scRNA-Seq), CRISPR editing, viral production, mammalian cell culture (including in vitro differentiation assays and generation of new cell lines), flow cytometry (analysis and sorting), processing of leukemic murine tissues and bioinformatic analysis skills are essential; however, we will consider all the skills and strengths that you have.

Prospective candidates are encouraged to contact Dr Nicola Wilson (nkw22@cam.ac.uk) directly when considering an application to discuss the project in greater detail.

Fixed-term: The funds for this post are available for 18 months in the first instance. 

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check.

To apply online for this vacancy and to view further information about the role, please click on the apply button above.

Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The closing date for applications is: 14th January 2024

The interview date for the role is: W/C 22nd January 2024

Please quote reference RB39594 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from University of Cambridge

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge