|£33,966 to £44,263 per annum
|28th November 2023
|2nd January 2024
About the Role
Plant Molecular Biologist; Plant Immunity
A fixed term contract BBSRC funded Research Fellow position is available in the Grant laboratory, a well-funded group working on a range of challenges in the plant immune field, including; systemic signalling, metabolic immunity, inter-organellular communication and the molecular basis of immune suppression.
We seek a highly motivated and enthusiastic molecular biologist, ideally with some cell biology expertise and experience in plant immunity to work on understanding the role nucleoside derivatives generated by plant disease resistance proteins in dictating the outcomes of plant-pathogen interactions using the model pathosystem, Arabidopsis thaliana -Pseudomonas syringae.
This project focusses on the Toll-Interlukin 1 (TIR) class of plant disease resistance proteins (TNLs) which have NADase activity leading to the production of variant cADP-ribose (vcADPR). Remarkably, pathogens deploy TIR domains to produce different v-cADPRs that interfere with plant immune signalling. This project will dissect how these contrasting TIR domain products impact the immune outcome. It involves collaborators in the USA, Hong Kong and Australia and deploys a range of pre-existing tools and techniques including real time imaging, RNAseq, CRISPR, genetically encoded reporters and targeted mass spectrometry to achieve this objective. Warwick has excellent facilities for this research including state-of-the-art imaging suite and one of the UKs leading Mass Spectrometry facilities.
Full details of the duties and selection criteria for this role can be found in the vacancy advert on the University of Warwick's jobs pages. You will be routed to this when you click on the Apply button.
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