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Research Assistant in the Department of Basic & Clinical Neuroscience

King's College London - Basic & Clinical Neuroscience

Location: London
Salary: £37,332 per annum, including London Weighting Allowance
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 1st December 2023
Closes: 4th January 2024
Job Ref: 080126
 
Job description

The postholder will contribute to the investigation of research questions and develop specific research projects under guidance from the Group Leader. Specifically, you will complete molecular biology assays and confocal imaging in cultured neuron, cell line and brain tissue.  You will also be required to:

  • Demonstrate the importance of your research in the form of intellectual property, novel techniques or findings that make a significant contribution to the field. 
  • Contribute to the dissemination of research findings.
  • Contribute to the training and supervision of junior staff.
  • Maintain equipment and organise biological samples.
  • Undertake any other reasonable duties that may be requested by the PI.

This post will be offered on a full-time, fixed-term contract to 31st October 2025.

Key responsibilities
  • In vitro experimental methods for protein assays  
  • Tissue collection and processing for protein quantification, immunohistochemistry and biochemistry
  • Advanced microscopy using confocal/super-resolution imaging
  • Quantitative image analytical software and statistical analyses
  • AAV gene transduction and expression

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post. 

Skills, knowledge, and experience 

Essential criteria  

1.       BSc/MSc in Neuroscience or an equivalent biological field  

2.       An ability to work independently and within a team 

3.       Experience and ability of protein assays from brain tissue and cell line (eg, immunoblotting, immunocytochemistry, PCR) 

4.       Experience of advanced microscopy using confocal/super-resolution imaging

5.       Quantitative image analytical software and statistical analyses

6.       AAV gene transduction and expression

7.       Attention to detail and high standards of accuracy in all work 

8.       Conscientious, organised with good time management skills  

9.       Willing to work occasionally during weekends and bank holidays 

Desirable criteria

1.   Experience of plasmid cloning 

2.   Knowledge of molecular mechanisms of neurodegenerative disease or synapse biology 

3.   Skill for super-resolution imaging

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