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PhD Studentship (Cancer Research UK-funded) - Exploiting Pleiotropic Roles of DNA-PKcs in advanced Prostate Cancer

Newcastle University

Qualification Type: PhD
Location: Newcastle upon Tyne
Funding for: UK Students, EU Students, International Students
Funding amount: £19,500 living expenses per annum + 100% of Home tuition fees paid
Hours: Full Time
Placed On: 12th February 2024
Closes: 29th February 2024
Reference: 8440F

Award Summary

100% of Home tuition fees paid and annual living expenses of £19,500/annum (full award).

Overview

Are you interested in investigating a key driver of advanced prostate cancer with a view to developing future therapeutics? Prostate cancer kills 12,000 men in the UK each year and requires new, more effective treatments. By therapeutically exploiting common genomic vulnerabilities we have the potential to develop more effective treatments without debilitating side-effects. Crucially, this project will combine contemporary in vitro and in vivo methodologies, including CRISPR knock-in and knockout approaches, to validate susceptibility biomarkers that will enable more effective treatment sequencing to enhance treatment outcomes.  

The successful applicant will undertake cross-disciplinary training in multiple molecular and cellular approaches and be an integral member of a multi-disciplinary team involving molecular biologists, immunologists and medicinal chemists together with both national and international collaborators. 

For further information about this project please contact luke.gaughan@ncl.ac.uk

Number Of Awards

1

Start Date

Monday 30th September 2024

Award Duration

4 years

Sponsor

Cancer Research UK

Supervisors

Dr Luke Gaughan https://www.ncl.ac.uk/bns/people/profile/lukegaughan.html 

Dr Emma Scott https://www.ncl.ac.uk/medical-sciences/people/profile/emmascott.html  

Dr Celine Cano https://www.ncl.ac.uk/nes/people/profile/celinecano.html 

Newcastle University Centre for Cancer 

Eligibility Criteria

You must have, or expect to achieve, at least a 2:1 Honours degree or international equivalent, in an appropriate subject, including: biochemistry, molecular biology or biomedical sciences. A further qualification such as an MRes is advantageous. 

We welcome applicants from all suitable candidates, but only home fees will be covered by Cancer Research UK. For international applications, please be advised that you will be expected to cover the additional fees charges. 

How To Apply

You must apply through the University’s Application Portal via the ‘Apply’ button above.

In ‘Course choice’ tab, put ‘Postgraduate Research’ in 'Type of Study', ‘Full Time’ in ‘Mode of Study’, ‘2024’ in ‘Year of Entry’, code ‘8440F’ in ‘Course Title’, blank in ‘Research Area’. Press ‘Search’, select ‘PhD Translational and Clinical Research (FT)’, and save selection. 

Either upload a document or write into ‘Personal Statement’. Put code ‘TC090’ in ‘Studentship/Partnership Reference’. When prompted for research proposal, select ‘Write Proposal’. Type in the title of the research project from this advert. A research proposal is not required. You can also upload a covering letter and CV, please state how your interests and experience relate to the project. 

Degree transcripts/certificates and, if English is not your first language, a copy of your English language qualification if completed must be uploaded.

Contact Details

For further information about this project please contact luke.gaughan@ncl.ac.uk 

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