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Research Fellow

UCL - Biosciences

Location: London, Hybrid
Salary: £42,099 to £50,585
Hours: Full Time
Contract Type: Permanent
Placed On: 20th February 2024
Closes: 4th March 2024
Job Ref: B02-06530

Biosciences is one of the world’s foremost centres for research and teaching in the biological sciences and one of the largest Divisions within UCL, undertaking a significant amount of research and teaching. The Division has a diverse portfolio addressing all areas of biology from protein interactions to cell function, organism development, genetics, population studies and the environment. Computational modelling approaches are frequently used alongside experimental research programmes and much of our research crosses traditional boundaries, including the relationship of biodiversity to the health of the planet. Activity is underpinned by high calibre science technology platforms and state of the art equipment. Educational activity includes a range of undergraduate programmes, an expanding number of Masters Programmes and a substantial number of postgraduate research students.

This is an exciting opportunity to join the group of Kristin! e Arnvig at UCL’s department of structural and molecular biology.

The project aims to resolve the role of riboswitch-regulation of glycine metabolism in different pathogenic mycobacteria including Mycobacterium tuberculosis.

The main purpose of this position is to be an active member of a research team assisting in the planning and delivery of research into riboswitch regulation of glycine metabolism in pathogenic mycobacteria. The role specifically focusses on the general microbiology and metabolomics of glycine metabolism.

Main duties include research in the Arnvig group including planning own day-to day activities and experiments, analysing data, and presenting results. The project includes, but is not limited to working in the CL3 lab, general biochemistry, metabolomics (LCMS), protein expression and purification (HPLC, FPLC) structural and functional protein characterization (NMR, ITC), reporter gene assays and microbiology. Experiments may include isotope work and you will need to undergo local training for CL3 work and for handling radioactive isotopes.

This is an open ended role funded for 12 months.

This appointment is subject to UCL Terms and Cond! itions of Service for Academic Staff. Please visit https://www.ucl.ac.uk/human-resources/policies/2021/jun/conditions-service-academic-stafff or more information.

If you have any queries about the role, please see contact details on the UCL job advert page.

You are a highly motivated and independent scientist, who can provide original contributions to the subject areas of mycobacterial metabolomics and enzymology. Knowledge of RNA biology and riboswitches an advantage. You have a PhD and postdoc experience in one of the relevant subject areas and a proven track record of working with mycobacterial proteins and metabolomics. Experience in CL3 work is essential.

You will assist the team in the development, planning and delivery of research funded by MRC.

You will be expected to produce independent and original contributions to the development of glycine metabolism in mycobacteria.

In addition to developing and conducting the research, you will communicate results as scientific papers and in scientific presentations at local, national, and international conferences.

As well as the exciting opportunities this role presents, we also offer some great benefits.

Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
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