Postdoctoral Research Scientist

About us:

At the Department of Physiology Anatomy & Genetics (DPAG) we undertake discovery science where we reassemble physiological processes at the molecular, cellular, tissue and systems level of organisation. In so doing we provide a bridge to translational medicine, and interface between physical and life sciences. We are committed not only to innovative research and the highest standard of teaching, but also to creating an inclusive and supportive working environment.

Overview of the role:

We are seeking a Postdoctoral Research Scientist (PDRS) to join the Swietach group. The ideal candidate will be an experienced cancer scientists with an interest and track record in metabolism. In this role, you will be responsible for undertaking research on metabolic heterogeneity in pancreatic cancer, implementing innovative assays to understand dynamic changes in metabolic profile, and how these affect cancer growth. The aim of the project is to unravel new vulnerabilities that could be targeted therapeutically.

This post is available from 02 December 2024 until 01 December 2027.

Key responsibilities:

• Manage academic research activities and associated project management, co-ordinate multiple aspects of work to meet deadlines
• Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate
• Receive training to innovate scientific techniques
• Use specialist scientific equipment in a laboratory environment
• Engage in the collaborative opportunity between the host departments
• Undertake the research plan on cell lines, including a series of animal experiments, with a view of seeking translational opportunities for future work.
• Contribute ideas for new research projects, develop ideas for generating research income.
• Collaborate in the preparation of scientific reports and journal articles and present papers and posters
• Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques
• Represent the research group at external meetings/seminars, either with other members of the group or alone

Selection criteria:

• Hold, or be close to completion of, a PhD/DPhil in a relevant field, such as biochemistry, molecular biology, cancer research
• Possess sufficient specialist knowledge in the area of metabolism and/or signalling
• Demonstrable, advanced-level experience in cell culture, including gene manipulation and handling multiple cell lines concurrently
• Have experience in performing genetic screens such as CRISPR screens, or implementing innovative methods to study metabolism, or in single-cell technologies
• Ability to manage own academic research and associated activities
• Previous experience of contributing to peer-reviewed publications
• Commitment to engaging with, and promoting awareness of, equality, diversity and inclusion and embedding these into your work

Informal enquiries about the role may be directed to the DPAG HR Team:  hr@dpag.ox.ac.uk 

DPAG’s Statement of Inclusion:

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. Our policies, practices and Respectful Behaviours Framework underpin this commitment.

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