Research Fellow - Postdoctoral researcher

Applications are invited for a motivated and self-driven postdoctoral researcher to join The O’Boyle Group based in The Department of Microbiology, School of Genetics and Microbiology, Trinity College Dublin.  The project will involve the development and in vitro testing of therapeutics against Crohn’s disease-associated Enterobacteriaceae. 

Inflammatory bowel disease (IBD) comprises distinct clinical subtypes, with unique microbial associations, pathological features and responses to treatment. Ileal Crohn’s disease (ICD) has the strongest association with over-proliferation of a specific family of bacteria, the Enterobacteriaceae. While their role in disease progression is poorly understood, they are considered an attractive target for therapies aimed at dampening IBD-associated inflammation. This project will involve the isolation and characterisation of opportunistic Enterobacteriaceae from intestinal biopsies, development of patient-derived organoids, metabolomics, metagenomics, advanced microscopy, dietary analysis, and classic microbiology. The project will be further supported by Public and Patient Involvement (PPI) whereby a team comprising inflammatory bowel disease patients and their family members will co-design elements of the research. 

The appointed postdoc will be based at The Moyne Institute of Preventative Medicine and will form part of a vibrant multidisciplinary collaborative team. 

Additional funding will be provided for conference attendance and professional development.

The anticipated start date is 1^st September 2025.  

Post title: Research Fellow - Postdoctoral researcher 

Post status: Four-year specific purpose contract, full-time

Salary: Appointment will be made at a position on the IUA scale commensurate with experience (IUA Scale PD1 [€46,305 - €52,863] or PD2 [€54,307 - €59,063])

Closing date: 11:59PM (Irish Standard Time), 31st May 2025

Full job description and application instructions: https://my.corehr.com/pls/trrecruit/erq_jobspec_details_form.jobspec?p_id=038229 

Informal enquiries may be sent to: Dr Nicky O’Boyle (oboylen1@tcd.ie) 

Trinity is an equal opportunities employer, and we encourage applications from talented people of all backgrounds to join our staff community. 

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