Postdoctoral Research Fellow

Full-time: 35 hours per week

Fixed-term: for 3 years

The opportunity:

This job post is for a postdoctoral research associate to conduct research on the role of two G-coupled receptors in the progression of difficult-to-treat acute myeloid leukaemia (AML).

The job holder will need to (i) study the biology of GPR56/GPR97 in leukemic cells (and in normal haematopoietic stem cells as a control), (ii) establish leukaemia cell lines and human iPSCs lacking one or both GPRs, and (iii) study their effects on haematopoietic cell function to identify mechanisms involved in AML progression and chemo-resistance.

This post is full-time (35 hours per week).

Any appointment above spine point 4 (i.e. UE07/35) on the scale may result in a reduced contract length than advertised due to budget restraint.

The salary for this post is £40,497 to £48,149 per annum.

Your skills and attributes for success:

• Appropriate degree, with relevant post-graduate research experience and accumulated knowledge.
• A PhD or equivalent professional qualification and/or experience in the field of normal and malignant haematopoiesis.
• PhD (or to be completed within 2 months of interview date) in an appropriate field.
• Experience on cell culture  (human primary cells, cell lines and human iPSCs).
• Strong expertise in multi-colour flow cytometry, CRISPR/Cas9 and molecular biology.

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