PhD Studentship: Metagenomic Methods Development for Public Health Genomics and Pandemic Preparedness

Metagenomics (the sequencing of all genetic material within a sample) offers the promise of being a single test to diagnose all clinical infections. By directly sequencing all nucleic acid from a clinical or environmental sample we can rapidly identify all organisms present including novel strains and newly emerged pathogens. Currently such methods are only available in specialist laboratories, each performing their own techniques that vary, due to differences in the types of samples (respiratory, blood, waste water, etc) or pathogens (bacterial, viral, fungal) of specific interest.

This project aims to optimize metagenomic workflows across sample types, developing integrated, sample-specific methodologies.

Collaborating with leading academic developers and front line metagenomics users, including the UKHSA’s Imported Fever Metagenomic Service, we will evaluate diverse approaches to establish best practices.

This studentship provides a molecular biologist with exceptional training in clinical and public health genomics, combining academic research with front-line public health intervention experience.

This project is part of an exciting new Doctoral Training Programme in Microbial Genomics for Health Protection in collaboration with the UK Health Security Agency (UKHSA). This is funded by NIHR as part of a Health Protection Unit in Public Health Genomics between the University of Birmingham and UKHSA. In addition to the extensive training offered to all PhD students at UoB, the cohort of students on this DTP will receive training and opportunities at both UoB and UKHSA in the area of public health genomics.

Applications of a two page CV and covering letter including your experience, suitability and motivation should be sent to hpru-phgenomics@contacts.bham.ac.uk by 31st July 2025 via the above 'Apply' button.  

Supervisors: Dr Joshua Quick – University of Birmingham, Steven Pullan – UKHSA.

Advert information