Laboratory Technician

The inflammatory neuropathies are paralysing conditions with potentially devastating consequences, yet their pathology is poorly understood. The Rinaldi laboratory has pioneered the use of myelinating co-cultures, based on human pluripotent stem cell derived neurons, to study these disorders. We have also started to investigate their underlying immunology and have secured major new funding from the MRC for a project entitled “Shaping a new classification and treatment era for the inflammatory neuropathies through precision immunophenotyping.” The group also has an interest in antibody discovery and in developing fluid biomarkers of peripheral nerve injury. The diagnostic lab runs an antibody testing service with an international reach to aid in the diagnosis and monitoring of both central and peripheral nervous system autoimmune diseases, receiving 100s of samples per week for clinical testing. 

 

You will be an experienced member of the team, providing technical and administrative support, to ensure the smooth running of the inflammatory neuropathy and the autoimmune neurology diagnostic laboratories. Your duties will include processing and cataloguing patient-derived samples, maintaining cell cultures (including of IPSC-derived neurons and primary immune cells), running immunoassays, and maintaining a database and other records. You will be responsible for ensuring the smooth day to day running of the laboratory and for providing support to less experienced team members. You will act as a key link between the inflammatory neuropathy research group and the autoimmune neurology diagnostic laboratory. 

 

You will have been educated to at least A-level or equivalent qualification in science and will have prior experience of working in a laboratory environment, with an ability to organise your own workload and take initiative when appropriate. Prior experience of cell-culture, protein production, and sample processing is desirable. Training will be provided for all required duties and procedures. 

 

For further details about the Inflammatory Neuropathy Research Group please see - https://www.ndcn.ox.ac.uk/team/simon-rinaldi

 

Informal enquiries to simon.rinaldi@ndcn.ox.ac.uk are welcome. 

 

Please click the 'Apply' button above to see the 'Job Description' for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply.

 

 

 

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