Research Assistant/Research Associate (Fixed Term)

We are seeking an enthusiastic, motivated individual for a position in the group of Professor Alan Warren, Department of Hematology in the Cambridge Institute for Medical Research at the Cambridge Biomedical Campus. You will join an exciting research programme investigating fundamental mechanisms of ribosome assembly, translational control and how defects in these processes drive cancer development. This post will involve the use of cutting edge biochemical, proteomic, next generation sequencing and ribosome foot printing technologies.

This position is available for an immediate appointment. Candidates must either have a PhD in a relevant biological subject or have submitted or about to submit their PhD thesis. Candidates must also have demonstrable expertise in biochemistry, cell biology and/or molecular biology. Relevant post-doctoral experience is desirable. High quality peer-reviewed publications and a keen interest in translational regulation are essential.

If you have an excellent background in biological sciences, are prepared to face intellectual challenges and wish to develop your scientific skills, we would like to hear from you. Applicants should have outstanding organisation and communication skills and work well as part of a team.

The funding for this position ends on 30th April 2030.

Applicants must have (or be close to obtaining) a PhD.

For recent publications see below:

Machado HE, Øbro NF, Williams N, Tan S, Boukerrou AZ, Davies M, Belmonte M, Mitchell E, Baxter EJ, Mende N, Clay A, Ancliff P, Köglmeier J, Killick SB, Kulasekararaj A, Meyer S, Laurenti E, Campbell PJ, Kent DK, Nangalia J, Warren AJ. Convergent somatic evolution commences in utero in a germline ribosomopathy. Nature Communications 14, 5092 (2023). https://doi.org/10.1038/s41467-023-40896-5. PMID: 37608017.

Jaako P, Faille A, Tan S, Wong CC, Escudero-Urquijo N, Castro-Hartmann P, Wright P, Hilcenko C, Adams DJ, Warren AJ. eIF6 rebinding dynamically couples ribosome maturation and translation. Nature Communications 13, 1562 2022. https://doi.org/10.1038/s41467-022-29214-7. PMID: 35322020.

Tan S, Kermasson L, Hilcenko C, Kargas V, Traynor D, Boukerrou AZ, N Escudero-Urquijo, Faille A, Rossmann M, Goyenechea B, Bertrand A, Moreil J, Alibeu O, Beaupain B,  Bôle-Feysot C, Fumagalli S, Kaltenbach S, Martignoles J-A, Masson C, Nitschké P, Parisot M, Pouliet A, Radford-Weiss I, Tores F, de Villartay J-P, Zarhrate M, Koh AL, Phua KB, Revesade B, Bond PJ, Bellanné-Chantelot C, Callebaut I, Delhommeau F, Donadieu J, Warren AJ* and Revy P*. Somatic genetic rescue of a germline ribosome assembly defect. Nature Communications (2021) Aug 19;12(1):5044. doi: 10.1038/s41467-021-24999-5. PMID: 34413298 *Joint Senior authors.

Informal enquiries to Alan Warren ajw1000@cam.ac.uk

To apply online for this vacancy and to view further information about the role, please click on the ‘Apply’ button above.

Interviews will be held in mid July 2025

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please quote reference SB46087 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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