PhD Studentship - TB Strain Effects on Resistance and Outcomes in England

This project will utilise the internationally unique pathogen genomic and associated meta data for all TB cases in the UK, numbering in the tens of thousands over more than a decade. This data set will be used to perform a comprehensive pathogen population analysis of TB in the UK, including routes of entry to the UK, onward transmission, geographic specific lineages and adaptations, including specific drug resistance and pathogenesis mutations. The project will combine classical microbial genomics with machine learning and AI analysis approaches to create the most in depth population analysis of TB this country.

This project is part of an exciting new Doctoral Training Programme in Microbial Genomics for Health Protection in collaboration with the UK Health Security Agency (UKHSA). This is funded by NIHR as part of a Health Protection Unit in Public Health Genomics between the University of Birmingham and UKHSA. In addition to the extensive training offered to all PhD students at UoB, the cohort of students on this DTP will receive training and opportunities at both UoB and UKHSA in the area of public health genomics. Applications of a two page CV and covering letter including your experience, suitability and motivation should be sent to hpru-phgenomics@contacts.bham.ac.uk (via the ‘Apply’ button above) by 31st July 2025.

Supervisors: Professor Alan McNally (a.mcnally.1@bham.ac.uk) - University of Birmingham, Dr Esther Robinson – UKHSA.

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