Research Assistant in Mass Spectrometry

The research assistant will be a member of a team researching mechanisms underlying obesity and metabolic diseases. The laboratory uses mass spectrometry to identify and measure peptides and proteins, and investigate how these molecules are involved in energy metabolism and how they can affect the health of patients with metabolic diseases.

The group has three mass spectrometers which the applicant will aid in running. A ThermoFisher Q-Exactive Plus Orbitrap with an Ultimate 3000 LC system which is used for untargeted peptidomics and proteomics experiments. A SCIEX 7600 ZenoToF instrument running in nanoflow for untargeted peptidomics and proteomics analyses. This system is used to generate proteomics and peptidomics datasets that are searched with the PEAKS Bioinformatics software package, and the results interrogated using the Perseus program.

The third system is a Waters TQ-XS triple quadrupole with an M Class LC system. The instrument has a normal source interface, an IonKey source and a nano source to cater for various throughput and sensitivity requirements.

The appointee will receive training in developing quantitative LC-MS methodologies for peptides and proteins, as well as performing peptidomic and proteomics analyses in clinical and preclinical matrices.

Limited funding: The funds for this post are available until 31 March 2029 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment. This appointment also requires a Research Passport application.

To apply online for this vacancy and to view further information about the role, please click 'Apply' above.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date: 27th June 2025

Interview date: to be confirmed

Please quote reference RG46265 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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