Molecular Simulations and Modelling Scientist (KTP Associate)

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
RxCelerate and Newcastle University are offering an exciting opportunity to facilitate discovery of new innovative therapeutics, by developing and testing a method for identification of unique, short-lived states of proteins.

You will be part of a Knowledge Transfer Partnership (KTP) project which aims to deliver methodology to computationally predict and subsequently experimentally validate "druggable" states in disease-linked proteins.

RxCelerate is a leading drug discovery and development platform contract research company based in Cambridge, UK. They are driven by a mission to improve patients' lives through scientific excellence and innovation. Rather than fitting to conventional drug discovery paradigms, RxCelerate specialise in bespoke experimental design with data-rich endpoints, maximising the chances of clinical success while reducing long-term costs. RxCelerate was founded in 2013 and employs around 100 people.

Based at RxCelerate you will be supported by an interdisciplinary team from Newcastle University, led by Dr Agnieszka K. Bronowska and Prof Wyatt Yue with expertise in Structural Biology and Computational Medicinal Chemistry. You will be also supported by a senior supervisor from RxCelerate.

Candidates should have a PhD in molecular simulations of biomolecular systems or related fields (e.g., computational biophysics, computational chemistry).

Benefits:

• Develop managerial skills and attend two residential managerial workshops (each of one-week duration).
• £4,000 personal training budget.
• The opportunity to lead a project, develop project management skills and improve long-term career prospects.
• Mentoring by a Knowledge Transfer Network Adviser.
• Full access to university resources to complete the project.
• Ability to work in a largely self-determined way, across the industry-academic partnership.
• Opportunities to develop both technical understanding and commercial awareness.
• The possibility of studying for a higher degree or undertaking professional development.

The KTP Associate will be an employee of Newcastle University but will spend most of their working time at the company’s premises at The Dorothy Hodgkin Building, Babraham Research Campus, Babraham, Cambridge, Cambridgeshire, CB22 3FH and when required at Newcastle University. As part of your responsibilities, you will be required to travel to Newcastle approximately twice per year to conduct experimental validation.

The KTP Associate will follow RxCelerate’s working hours and holiday procedure. Your working week will be 37.5 hours. The shift pattern is Monday- Friday and there is flexibility within the core hours. Annual Leave applicable to this role is 25 days plus bank holidays.

Although the contract is fixed-term for a duration of 2 years, more than 70% of KTP staff gain a permanent job offer by their KTP company.

For more information or informal enquiries, please contact Dr Agnieszka Bronowska at Agnieszka.Bronowska@newcastle.ac.uk or Prof Wyatt Yue at Wyatt.Yue@newcastle.ac.uk.

For further details on the Faculty of Science, Agriculture & Engineering please visit our web page at: https://www.ncl.ac.uk/sage/.

For further details about Knowledge Transfer Partnerships please visit the web page at: http://www.ktp-uk.org/.

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