Research Associate in Image Analysis, Big Data and Epidemiology

University of Bristol - Bristol Medical School

Location:	Bristol
Salary:	£38,249 to £44,128 Grade I / Pathway 2, per annum
Hours:	Full Time
Contract Type:	Permanent

Placed On:	24th June 2025
Closes:	8th July 2025
Job Ref:	ACAD108168

The role

The University of Bristol is seeking a Research Associate to work with Dr Ben Faber on a Wellcome Trust-funded project entitled ‘Utilising large joint structural phenotypes of osteoarthritis for enhanced disease prediction and novel treatment target discovery.’ The primary aim is to leverage imaging and genetics to identify novel treatment targets for osteoarthritis. Applicants are sought who have experience with UK Biobank imaging data and epidemiological skills.

What will you be doing?

The successful candidate will work extensively with UK Biobank dual-energy X-ray absorptiometry scans in UK Biobank.
They will be expected to be adept at analysing hip and knee images to obtain accurate measures of joint shape and radiographic osteoarthritis.
They will be expected to be able to use advanced coding methods in Python, R and Stata to develop and curate a data set of over 240,000 scans across 70,000 individuals.
Epidemiological analyses will be used to identify novel relationships between structural phenotypes of osteoarthritis and clinical outcomes.
Genetic epidemiology will be used to conduct genome-wide association studies of imaging features of osteoarthritis.

You should apply if

Considerable experience (> 1 year) of analysing UK Biobank DXA imaging data
Proficient at using Statistical Software e.g. Stata, R, Python
Experienced at analysing Hospital Episode Statistic data and other forms of electronic healthcare records (e.g. OPCS3 & OPCS4)
In depth understanding of osteoarthritis and risk factors for disease
Experienced at handling and curating large datasets
Well organised and able to work to independently
Ability to identify technical problems, in collaboration with the project’s PIs, and discuss to identify solutions
Track record of collaborating across institutions to deliver complex research projects
Publications in the field

Additional information

Contract type: Open-ended with 3 years of funding from the start date

This advert will close at 23:59 UK time on 08/07/2025

For informal queries please contact: Ben Faber – ben.faber@bristol.ac.uk

Our strategy and mission

We recently launched our strategy to 2030 tying together our mission, vision and values.

The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people - because diversity of people and ideas remains integral to our excellence as a global civic institution.

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