Postdoctoral Project Research Scientist

Location: The Francis Crick Institute, Midland Road, London

Salary: From £45,500 with benefits, subject to skills and experience.

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role 

Our research is committed to advancing our understanding the biology of lung tumour evolution based around analysis of next generation sequence (NGS) data and the tumour microenvironment from the TRACERx longitudinal lung cancer program. Leveraging genomic, transcriptomic and epigenomic sequencing as well as spatial immunophenotyping data from patient samples, our aim is to trace the intricate evolutionary trajectories of lung tumours across space and time. This work will unveil the key drivers of cancer progression, immune resistance mechanisms, and potential vulnerabilities within the tumour landscape.

As a Postdoctoral Project Research Scientist in the Swanton lab, your main responsibilities will be to work with the informatics team on TRACERx project, whilst also contributing to other projects throughout the lab. If you have experience in Bioinformatics, are fluent in R or Python as well as experience in evolutionary or cancer biology, we would love to hear from you 

What you will be doing  

As a Postdoctoral Project Research Scientist at the Crick, you responsibilities will be:  

• To decipher evolutionary mechanisms during lung cancer initiation and progression.
• To employ novel informatics techniques based on evolutionary principles to the analysis of tumour subclonal evolution.
• To understand cancer biology and the relevant literature sufficiently to take own ideas forward as lead author on new projects.
• To work within the informatics team of the TRACERx and TRACERx EVO programs.
• To record all experiments and code in an accurate timely, clearly presented and reproducable manner, and use this to prepare data summaries and reports as and when required. 

About you

You will have 

• PhD
• Previous experience with cancer genomics NGS data
• Fluent in R or Python
• Evidence of significant contribution to high impact publications
• Experience with HPC environments
• Experience of collaboration with clinicians and wet lab scientists or work within a multi-disciplinary environment 

Please see the full job description here. 

See more about the lab here. 

About Working at the Crick

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact weronika.kucala@crick.ac.uk

To read more about our EDI approach, click here.   

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

To apply for this role, please click on the 'Apply' button above.

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