Location: | Cambridge |
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Salary: | £37,174 to £45,413 |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 31st July 2025 |
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Closes: | 8th August 2025 |
Job Ref: | RG46806 |
The laboratory of Professor Susan Ozanne (https://www.mrl.ims.cam.ac.uk/staff/professor-susan-ozanne) is seeking a postdoctoral research associate who has experience in isolation and characterisation of extracellular vesicles (EVs) from a range of sources as well as high content microscopy and cardio-metabolic phenotyping in rodent models. Our main research interest is in understanding how obesity and impaired glucose tolerance during pregnancy impacts on offspring cardio-metabolic health. We are particularly interested in how maternal obesity/GDM disrupts normal communication between the placenta and maternal vasculature via placental-derived EVs to contribute to impaired vascular physiology. The person appointed to this post will (i) characterize the miRNA and protein content of placenta EVs from obese vs. control pregnancies in both fetal sexes; and (ii) determine the biological impact of placental EVs on vascular biology in-vitro and in vivo.
Key responsibilities
Scientist with experience in profiling of microRNA and protein content of extracellular vesicles isolated from various sources. Applicants will have the following responsibilities:
Other information
This position is based at the MRC Metabolic Disease Unit within the Institute of Metabolic Science (https://www.mrl.ims.cam.ac.uk/) which provides a highly collaborative and stimulating environment.
Proposed start date: 1st September 2025. Informal inquiries about this position should be directed to Prof Susan Ozanne at seo10@cam.ac.uk with reference number RG46806 in the subject line.
Fixed-term: The funds for this post are available until 28th February 2026 in the first instance.
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Applicants must have (or be close to obtaining) a PhD.
Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £34,132) moving to Research Associate (Grade 7) upon confirmation of your PhD award.
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Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
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