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Research Fellow in Electron Microscopy

University of Leeds

Location: Leeds
Salary: £41,064 to £48,822 per annum (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 9th September 2025
Closes: 16th September 2025
Job Ref: FBSBM1221

Are you an ambitious researcher looking for your next challenge? Do you have an established background in Structural Biology, particularly Cryo-Electron Microscopy (cryo-EM)? Do you want to further your career in one of the UKs leading research-intensive Universities?

Based in the laboratories of Prof Stephen Muench and Dr Charlie Scarff at the Astbury Centre for Structural Molecular Biology, you will join a vibrant team working together on an exciting project deciphering the myosin mechanochemical cycle through time-resolved cryo-EM.

The project is funded for 3 years by the Biotechnology and Biological Sciences Research Council (BBSRC) and will involve developing time resolved cryo-EM to trap the molecular motor myosin in a series of different states to provide a step change in our understanding of how this machine functions. Elucidating the function is key to unlocking why certain mutations can cause disease such as early onset cardiac disease (through the muscle myosin protein) and how small molecules can modulate the function. Exceptional facilities and training are available in Leeds to support the project, including two Titan Krios electron microscopes equipped with the latest detectors.

You should have a PhD (or close to completion) in structural biology or a closely allied discipline, with experience in cryo-EM, as well as protein expression and purification.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences has recevied a prestigous Silver award. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information. 

Salary Requirements of the Skilled Worker Visa Route

Please note that this post may be suitable for sponsorship under the Skilled Worker visa route, but first-time applicants might need to qualify for salary concessions. For more information please visit: www.gov.uk/skilled-worker-visa.

For research and academic posts, we will consider eligibility under the Global Talent visa. For more information please visit: www.gov.uk/global-talent.

What we offer in return

  • 26 days holiday plus approx. 16 Bank Holidays/days that the University is closed by custom (including Christmas) – that’s 42 days a year!
  • Generous pension scheme plus life assurance – the University contributes 14.5% of salary.
  • Health and Wellbeing: Discounted staff membership options at The Edge, our state-of-the-art Campus gym, with a pool, sauna, climbing wall, cycle circuit, and sports halls.
  • Personal Development: Access to courses run by our Organisational Development & Professional Learning team.
  • Access to on-site childcare, shopping discounts and travel schemes are also available.

And much more!

To explore the post further or for any queries you may have, please contact:

Prof Stephen Muench

Email: S.P.Muench@leeds.ac.uk

Dr Charlie Scarff

Email: C.A.Scarff@leeds.ac.uk

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