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Postdoctoral Scientist in RNA and Peptide neoantigen Molecular and Functional Informatics

University of Oxford - Sir William Dunn School of Pathology

Location: Oxford
Salary: £39,424 to £47,779 p.a. with discretionary range to £53,483 p.a.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 1st October 2025
Closes: 31st October 2025
Job Ref: 182281

We are seeking a highly motivated post-doctoral researcher with recent doctoral and post-doctoral experience that bridges across research areas that include genomic informatics, RNA regulation, neoantigen prediction, pMHC-TCR molecular and function immuno-oncology. The post involves working at the interface of computational informatics and molecular immunology in relation to cancers with driver translocations. The post is funded by a collaborative grant that aims to develop the basic science and experimental basis for translation to personalised mRNA vaccines for rhabdomyosarcoma, a rare cancer in children and young adults with unmet need associated with PAX3/7:FOXO1 translocations. The post-holder will be located at the Sir William Dunn School of Pathology and must be able to work independently within a multi-disciplinary research group and in collaboration with key project partners in the Centre for Immuno-Oncology in the Nuffield Department of Medicine (Dr Felipe Galvez-Cancino).

The post-holder will be responsible for managing their own academic research, adapting existing and developing new scientific techniques and experimental protocols. You will work to identify, develop, modify and apply the necessary techniques to achieve the goals of the project. The post-holder should be able to present detailed research proposals to senior researchers, undertake comprehensive and systematic literature reviews and write up the results for publication in peer-reviewed journals, as well as present findings at external meetings, funder organisations and seminars.
 
The post-holder should either hold, or be very close to completion of, a PhD/DPhil in a subject relevant to the post preferably with experience equivalent to a post-doctoral level. You should have expertise in genomic and molecular computational-bioinformatic approaches, as well as direct experience with laboratory molecular and cell biology techniques with respect to either cancer or immunology. You should have proven skills in working independently to solve experimental problems and be capable of high-quality research as demonstrated by significant research outputs through publications, patents and conference proceedings.
 
This is a fixed-term appointment available for up to 30 months. If you are interested in this role, and have the skills and experience we are looking for, please apply online. You will be required to upload a CV and supporting statement as part of your online application. For further details, please contact Prof Bass Hassan via email: bass.hassan@path.ox.ac.uk.
 
The closing date for applications is 12.00 midday on Friday 31 October 2025. Interviews will be held as soon as possible thereafter.
 
At the Dunn School we are committed to supporting the professional and career development of our postdocs and research staff. To help them thrive and achieve their ambitions, we have created a comprehensive range of opportunities and initiatives designed to provide an exceptional launchpad for their future careers.
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