Postdoctoral Project Research Scientist

Location: The Francis Crick Institute, London

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role 

We are looking for a Postdoctoral Project Research Scientist to join the Ciccarelli Lab.

The lab is dedicated to uncovering the fundamental drivers of cancer evolution, combining cutting-edge computational methods with innovative wet-lab approaches. Our long-term goal is to understand how cancers emerge, progress, and respond to therapy, with a primary focus on gastrointestinal cancers.

We take a multi-disciplinary, collaborative approach, bringing together computational biologists, experimental scientists, and clinical partners. Every project is team-driven, offering a dynamic research environment where computational and experimental expertise come together to generate transformative insights. 

The role involves developing and optimizing the assay to maximize sensitivity and specificity using deep learning, spatial biology and digital pathology. You will validate the marker’s predictive power across multiple cancer types beyond colorectal cancer, broadening its clinical impact. This position offers the opportunity to collaborate closely with other Ciccarelli lab members and the Francis Crick Institute Scientific Technology Platforms, gaining access to world-class resources and expertise. 

This is a unique opportunity to drive forward a project with clear translational potential, bridging computational approaches, digital pathology, and clinical applications. You will be at the forefront of efforts to deliver a tool with the power to shape precision cancer immunotherapy strategies. 

What you will be doing 

You will be responsible for: 

• The development of an assay to predict response to cancer immunotherapy
• Leading your project and contribute to other projects on a collaborative basis
• Providing specialist advice and training to other members of the lab.

About you  

• PhD in Molecular Biology, Genetics, Pathology or in the final stages of PhD submission
• Knowledge and experience in R and Python computer coding
• Knowledge in tissue histology
• Expertise in immunostaining and tissue imaging
• Track record of writing papers as evidenced by publications or submitted manuscripts
• Evidence of data presentation at scientific meetings 

Please see the full job description here. 

About Working at the Crick 

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact people@crick.ac.uk 

To read more about our EDI approach, click here.   

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

To apply for this role, please click on the 'Apply' button above.

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