Post-Doctoral Research Associate

The Opportunity:

We seek a postdoctoral researcher to carry out a research project to investigate novel methods to make immune-cold colorectal cancer responsive to immunotherapy.  

A Cancer Research UK funded postdoctoral position is available in the lab of Dr Kevin Myant (https://institute-genetics-cancer.ed.ac.uk/research/research-groups-a-z/myant-group). The project aims to investigate the mechanisms of how targeting RNA splicing can activate immune responses in immune-cold colorectal cancer. The project will use immune-competent mouse models, patient derived human organoid models and RNA mapping technologies to determine how RNA splicing disruption activates innate and adaptive immune responses. We will utilise this data to develop novel therapeutic approaches to enhance the efficacy of immunotherapies in this disease. It would be ideally suited to a researcher with a background in immune-oncology, RNA biology and innate and adaptive immunity. For more information, please contact Dr Kevin Myant (kevin.myant@ed.ac.uk).

This post is fixed-term (for 36 months) with the potential for a further 3-year extension based on the meeting of key objectives and full-time (35 hours per week).  

The salary for this post is at Grade UE07: £41,064 to £48,822 per annum.

Your skills and attributes for success:

• A PhD in cancer biology or a related biomedical field.
• Previous evidence of successful project completion, in particular first author publications.
• Experience working with animal cancer models and organoid culture systems.
• Bioinformatic experience, in particular RNAseq analysis or experience of long read technologies.
• Ability to communicate complex information clearly.

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