MRC Postdoctoral Research Scientist LMS 2729

Fixed term (3 years)

London, UK

About us

The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. We are proud to launch our new Team Science initiative, marking a bold step toward a more collaborative, challenge-driven model of research.   

Team Science

Scientific breakthroughs rarely come from isolation—they emerge when brilliant minds connect. Our Team Science approach is more than just multi-disciplinary; it’s a fundamentally different way of working. We foster deep collaboration across fields, institutions, industry, and society to tackle questions that no one could answer alone. As a postdoc, you’ll be part of a dynamic environment that values your individual expertise while amplifying it through shared infrastructure, collective ambition, and interdisciplinary innovation. 

About the role

A talented and self-motivated postdoctoral researcher is required to employ a combination of cellular systems of senescence and develop assays to evaluate the effect of nucleic acid-sensing pathways (e.g. cGAS/STING, RIG-I, MDA5 and others) using functional genomics on senescent phenotypes and the interaction of senescent and immune cells. As part of the project, you will develop sophisticated co-culture systems to evaluate the interaction of senescent and immune cells in the context of ageing. The successful candidate will integrate expertise in the culture of primary cells and organoids, knowledge on molecular, cellular biology, immunology and functional screens. 

About you

We are seeking an enthusiastic and ambitious postdoctoral scientist with a PhD in Cell Biology, Molecular Biology, or Immunology, and experience with functional genomics (CRISPR, RNAi). The ideal candidate will have a proven track record of publishing scientific results in peer-reviewed journals, including one first-author paper. 

What we offer

As well as the exciting opportunities this role presents, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme.  Please follow this link to find out more - Benefits 

How to apply

For full details of the post and to complete an online application, please click on the 'Apply' button above and upload your CV, names and contacts of two scientific references, along with a cover letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Please quote reference number LMS 2729. 

Applicants are encouraged to review the brochure and our LMS website for additional information in the Team Science project. 

Please note that applications may be reviewed by both LMS and Imperial staff 

Closing date: 31 December 2025 

*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two and £1,800 in year three.