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Senior Research Fellow in Tuberculosis

University of Oxford - Life and Mind Building, South Parks Road, Oxford, OX1 3PS

Location: Oxford
Salary: £65,336 to £75,439 per annum : Research Grade 10 (with a discretionary range up to £84,663), inclusive of a pensionable Oxford University Weighting
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 8th December 2025
Closes: 7th January 2026
Job Ref: 183588

About the role

The Ineos Oxford Institute for Antimicrobial Research (IOI) is seeking to recruit a Senior Research Fellow in antituberculosis drug discovery and development. This is an exciting opportunity to pursue an independent programme of research in this critical area and to join Oxford University’s Tuberculosis Grand Challenge (https://www.ineosoxford.ox.ac.uk/ioi-grand-challenge-tuberculosis).

Tuberculosis is a leading cause of human morbidity and mortality, and an impediment to economic and social development in many regions of the world. The causative agent, Mycobacterium tuberculosis, is increasingly resistant to the available treatments and, as such, a major contributor to the global antimicrobial resistance burden. Consequently, there is an unmet medical need for new, better tolerated and more potent drugs to help reverse the pandemic and to improve global health.

The IOI was established in 2021 to provide innovative solutions to the global problem of antimicrobial resistance (AMR) that threatens our existing way of life. With ~90 staff, IOI is expanding its research portfolio and invites applications for a Professorial Research Fellow in tuberculosis drug discovery and development.

About you

Candidates with experience in molecular mycobacteriology, Crispr-Cas technology, drug target discovery and target validation, assay development, cellular and animal models of tuberculosis infection, DMPK, structure-activity-relationship analysis and preclinical drug development are particularly encouraged to apply.

Fellows will have the opportunity to establish their group in a state-of-the-art facility, the recently opened Life and Mind Building (https://lifeandmind.web.ox.ac.uk/) and will benefit from  a generous start-up-package to enable them to conduct world class research immediately upon arrival.

How to apply

The University of Oxford is committed to equal opportunity, and to being a place where everyone belongs and is supported to succeed. We recognise how the diversity of our community enriches our ability to deliver on our academic mission.

We welcome applications from individuals from all backgrounds, including those under-represented within higher education. No applicant or members of staff shall be unlawfully discriminated against on the basis of age, disability, gender reassignment, marriage or civil partnership, pregnancy or maternity, race, religion or belief, sex, or sexual orientation.

This post is full time and available immediately.

The closing date for applications is 12.00 noon on Wednesday 7th January, interviews are likely to be scheduled for late January. Applications for this vacancy are to be made online via our e-recruitment system. Applications (Arial font size 11, 1.15 line spacing) should include a personal statement and summary of the project (each one page), CV including publications, patents and grants (where applicable), and a detailed research programme (maximum 5 pages), and names of two referees.  Please send as a single PDF file.

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