Scientific Officer/Higher Scientific Officer - Drug Metabolism and Pharmacokinetics

Key Information

Salary: Commencement on the salary range is subject to comparable skills and experience. 

Reporting to: Angela Hayes

Duration of Contract: Fixed Term until September 2027

Hours per week: 35 hours per week (Full Time)

Job Details

Under the guidance of Angela Hayes, we are seeking to recruit a skilled Scientific Officer/Higher Scientific Officer to join the Drug Metabolism and Pharmacokinetics (DMPK) team. The post holder will contribute their expertise to advance pre-clinical drug discovery projects. The successful candidate will play a key role in developing, running and reporting in-vitro DMPK assays and performing in-vivo bioanalysis in line with Good Clinical Practice (GCP) guidelines to evaluate the pharmacokinetics and metabolism of potential new anticancer drugs.

The post holder will also interpret analytical data using PK software to calculate pharmacokinetic parameters. Additionally, the candidate will be required to collate, interpret data and report results to both internal project teams and external collaborators. The role involves extensive use of various Liquid Chromatography-Mass Spectrometry (LC-MS) methodology. This is an opportunity to contribute to life changing drug discovery in a highly collaborative environment.

About you

The ideal candidate will have a BSc in Pharmacology/Toxicology, Analytical Chemistry or related subject. Laboratory experience, preferably with LC-MS and in a DMPK environment is highly desirable. We are looking to appoint an enthusiastic problem solver to work in an interdisciplinary environment towards the goal of developing improved cancer therapeutics. The successful candidate will have the ability to work independently and as part of a team, maintaining attention to detail and keeping appropriate records. The ability to work within the guidelines of Data Protection, and Good Clinical Practice is essential. 

Department/Directorate Information

The Centre of Cancer Drug Discover part of the Division of Cancer Therapeutics, is a world-leading multidisciplinary 'bench to bedside' research centre. With around 150 scientists working together, we are dedicated to discovering and developing innovative cancer therapeutics that make a meaningful difference to patients' lives.

Our mission is clear: to identify high-quality drug candidates for validated biological targets and progress them into clinical trials. To achieve this, we bring together all the scientific disciplines required for success. Our biologists collaborate closely with world-class chemists and drug metabolism experts, focusing on innovative molecular targets emerging from cutting-edge genomics and cell biology research.

This is an exciting and fast-moving area of research, offering you the chance to work in a collaborative, inclusive environment, using state-of-the-art technologies and equipment to address some of the most significant challenges in oncology.

What we offer

• A dynamic and supportive research environment
• Access to state-of-the-art facilities and professional development opportunities
• Collaboration with leading researchers in the field
• Competitive salary and pension

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Angela Hayes via email on Angela.Hayes@icr.ac.uk.

Please apply via the ‘Apply’ button above.

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