Research Fellow in Developing Immunocompetent Animal-free Models of Bowel Cancer

Fixed-term – for 24 months

Full time – 37 hours per week

The School of Biosciences and Chemistry are looking to appoint a Research Fellow in the Biomolecular Sciences Research Centre, working on a project funded by the Humane Research Trust to develop animal-free models for the testing of new immunotherapies in the treatment of bowel cancer. You will contribute to an ongoing programme of research geared towards the use of “human tissue to model human disease”, promoting the development of new methods to replace the use of animals in medical research and delivering solutions that are both more humane and support better scientific in an area where current models have poor translation into patients with bowel cancer.

You will take the lead on liaising with clinical collaborators, collection of clinical material, processing and development of cell models using patient-derived material. You’ll be supported to develop your own interests in this field, with a view to developing your own independent research career. You’ll work in a team committed to producing high quality research outputs in the form of academic publications, conference presentations, and lead in a field with growing influence over governmental policy around humane medical research.

We are seeking a candidate with experience in cell biology and practical skills in microscopy and flow cytometry, preferably in the context of advanced models such as 3D matrix scaffolds and organoids. Knowledge of cancer biology would be desirable, and an up-to-date interest in cancer treatments such as immunotherapy would also be an advantage.

Experience working with primary clinical samples – including tissue and blood samples - would also be an advantage, and a commitment to flexible working patterns around sample availability is essential. Knowledge of working within the Human Tissue Act and evidence of good record-keeping are also key skills, as is experience working within inter-disciplinary teams in order to support the clinic-model pipeline.

We offer a diverse range of benefits and opportunities to pursue a rewarding and fulfilling career in a supportive environment.

You will be contractually enrolled into the Teachers’ Pension Scheme (TPS) – one of the largest and most generous defined benefit pension schemes in the country.

Find out more about the TPS

If you are, or have been, a recent member of the Universities Superannuation Scheme (USS) directly prior to joining us, you can choose to opt out of the TPS and remain in the USS. Please contact the Pensions team to discuss options available.

For this job we particularly welcome applications from minority ethnic applicants who are underrepresented in this area/ this type of job at Sheffield Hallam.

The role is not eligible for sponsorship under the Skilled Worker route so if you are an international applicant, you will need to ensure you have an appropriate visa to evidence the necessary right to work in the UK.

We welcome applications for flexible working arrangements. 

To find out more, take a look at our guide to applying.

We recommend you download the job description and person specification when you apply, as this will not be available once the job has closed.

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