Research Associate - Stem Cell Biology

We are seeking an independent and motivated Research Associate to work in the laboratory of Professor Ivana Barbaric at the University of Sheffield.

Our group has been studying the causes of aneuploidy in human pluripotent stem cells (hPSCs) and the implications of recurrent aneuploidies for applications of hPSCs in regenerative medicine. In the advertised project, we will utilise our well-curated aneuploid hPSC lines and combine them with hPSC-based embryo models to determine the impact of aneuploidy on cell survival, differentiation and patterning during early development and identify pathways dysregulated by aneuploidy. We expect that these results will provide mechanistic insights into effects of aneuploidy on human embryo development and provide future strategies for minimising the impact of aneuploidy on embryogenesis.

Applicants must have a PhD (or be close to completion / have equivalent experience) in cell or developmental biology, or a related field. Experience with culture and differentiation of human pluripotent stem cells (hPSCs) is also essential. Applicants must be self-motivated, well-organised, highly independent, and willing to work with other members of the existing research team. Excellent communication, written and interpersonal skills are essential.

The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university.

We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more.

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