Post-Doctoral Researcher - Genome Integrity

We are recruiting a Postdoctoral Researcher to join the lab of Professor Adrian Saurin in the Department of Genome Integrity at The University of Dundee. This is a fixed-term appointment for 36 months in the first instance, with possible extension thereafter.

We are looking for a talented ambitious postdoctoral researcher to join an 8-year Wellcome-funded team project. The goal is to study a fundamental property of all phosphorylation sites, for which almost nothing is currently known: the speed at which individual molecules are phosphorylated and dephosphorylated over time. The interdisciplinary team assembled to tackle this has expertise in kinase and phosphatase signalling (Prof Adrian Saurin, University of Dundee), mass spectrometry (Dr Tony Ly, University of Dundee) and biochemical reconstitutions (Prof Andrea Musacchio, Max Planck Institute, Dortmund). These approaches will be used to study how dynamic phosphorylation sites that continually “flash” on and off regulate key signalling properties during mitosis. A major goal is to understand how these sites are important to regulate kinetochores and chromosome segregation, and why this may fail to drive cancer progression. This position is primarily to use cell biology and advance microscopy techniques, but there is the possibility for the candidate to transit between labs and learn mass spectrometry and biochemical reconstitutions.

For further information about this position please contact Prof Adrian Saurin at a.saurin@dundee.ac.uk. To find out more about the lab and the project in general please visit www.saurinlab.com. In particular, check out the philosophy section to learn more about lab culture.

Your priorities will include:

• Examining how mitosis is regulated by dynamic phosphorylation sites.
• Using a wide range of cell biology approaches, including microscopy and single-molecule imaging.
• Using mammalian cell types and in vitro biochemical reconstitutions.
• Working effectively and collaboratively as part of an interdisciplinary team.

Who we are looking for:

• A highly-motivated and ambitious postdoctoral researcher with a passion for science.
• A candidate with a Ph.D. in relevant scientific area, with at least one first author publication.
• A strong scientific background in cell biology with experience of relevant techniques and/or working on the mitosis.
• Candidates who are motivated, honest, hard-working, collaborative and possess excellent organisational skills

The University of Dundee is rated 1^st in Scotland and 2^nd in the UK for Medicine (The Times & Sunday Times Good University Guide 2026) and the top university in the UK for Biological Sciences (Research Excellence Framework 2021).

The University of Dundee is a signatory of the Researcher Development Concordat and is committed to enhancing the research environment and culture. Engagement and support of activities which assist the researcher development agenda at the University is therefore essential. The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

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