Research Associate (Fixed Term)

Applications are invited for an enthusiastic and motivated Research Associate to join the Laboratory of David Owen and Bernard Kelly at the Cambridge Institute for Medical Research. Our work combines cell biology, structural biology and biochemistry/biophysics to build a deep, integrated understanding of intracellular trafficking mechanisms, with a particular emphasis on cargo sorting in the endocytic system. The successful candidate will study the cell biology of receptor trafficking between the plasma membrane and endosomes.

All applicants must hold at minimum a PhD in cell biology/biochemistry and have prior extensive experience with (a) confocal, epifluorescence and live-cell microscopy to study transmembrane protein trafficking in cultured cells (with associated use of statistical analysis), (b) cell line engineering (creating stable cell lines by viral transduction) and carrying out RNA depletion (siRNA/shRNA) and (c) immunoprecipitation, western blotting, FACS, and protein biochemistry techniques. In-depth knowledge of endosomal function and morphology and/or experience with cellular immunoelectron microscopy and/or super-resolution microscopy would be greatly advantageous.

The Cambridge Institute for Medical Research (CIMR) is located on the Cambridge Biomedical Campus and it is a collaborative institute at the interface between fundamental research and the clinic, with a mission to determine the molecular mechanisms of disease in order to advance human health.

This full-time fixed-term post is available for 2 years.

Informal enquiries to Bernard Kelly btk1000@cam.ac.uk

To apply online for this vacancy and to view further information about the role, please visit: www.jobs.cam.ac.uk/job/55801.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The interview for the role is to be confirmed

Please quote reference SG49944 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Advert information