Principal Computational Biologist

About the role:

We are currently looking for a passionate and motivated Principal Computational Biologist to work collaboratively within the Computational Biology Team. The Computational Biology Team is closely linked to the core facilities within the CRUK Manchester Institute, which operate a wide range of advanced genomics technologies, including Illumina deep sequencing data, mass spectrometry, and advanced imaging.  The team is responsible for the experimental design, validation, pre-processing, analysis and interpretation of datasets generated by these core facilities and, most importantly, provides analysis services to the research groups within the Institute. The team work collaboratively to provide high-quality computational biology to support different groups’ research programmes and make use of a dedicated on-site High Performance Computing Facility managed by a separate Scientific Computing Team.

About you:

You will have a background in Systems immunology/Computational Biology/Bioinformatics/Biostatistics (or related discipline) along with relevant experience in analysing immunological data sets. You will have excellent interpersonal skills with the ability to establish effective working relationships and build networks. You will have high levels of organisational and time management skills and the ability to prioritise and handle competing demands and work to deadlines with limited supervision. You should have a PhD in Systems Immunology, Bioinformatics, Computational Biology or Biostatistics OR a relevant postgraduate degree in Systems Immunology, Bioinformatics, Computational Biology or Biostatistics along with significant relevant experience in analysing large immunological data sets.

Why choose Cancer Research UK Manchester Institute?

The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research.  The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world.  In spring 2023 the Institute moved into the new Paterson Building, a £150 million flagship purpose-built biomedical research centre directly attached to The Christie NHS Foundation Trust (www.christie.nhs.uk), in South Manchester.

We are partnered with The Christie NHS Foundation Trust, one of the largest cancer treatment centres in Europe.  These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

Take a look around the Institute

How to apply?

To apply for this position please visit our website:  https://www.cruk.manchester.ac.uk/careers/. Please ensure you detail the names of three referees and ensure you submit your application before the closing date specified.

For any informal enquiries about this post, please contact Sudhakar Sahoo sudhakar.sahoo@cruk.manchester.ac.uk

Please note this vacancy will close for applications at 18:00 hours on the closing date specified.

Closing date: Sunday 2 August 2026.

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