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Research Portfolio Manager

The Francis Crick Institute

Location: London
Salary: From £48,955
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 5th August 2026
Closes: 19th August 2026
Job Ref: R2803
 

Contract:             Fixed Term, Full Time

We are seeking an experience Research Portfolio Manager to lead the management of the Crick’s portfolio of clinical research studies.

You will oversee projects from study set-up through to completion, supporting researchers to navigate regulatory requirements, coordinate stakeholders and deliver high-quality research involving human participants. Working across multidisciplinary teams, you will play a key role in driving study delivery, maintaining compliance and continually improving our clinical research processes.

This is an exciting opportunity for an experienced clinical research professional who enjoys project management, stakeholder engagement and improving how research is delivered within a world-leading biomedical research institute.

Key Responsibilities

These include but are not limited to:

  • Leading a portfolio of clinical research studies across the full study lifecycle.
  • Managing study set-up, regulatory approvals, monitoring, risk management and project delivery.
  • Coordinating with scientists, NHS partners, participating sites and external collaborators to ensure successful study delivery.
  • Leading IRAS submissions, sponsorship assessments and Trial Master File management.
  • Monitoring study progress, identifying risks and providing clear project reporting.
  • Developing and improving governance processes, SOPs and researcher guidance.
  • Supporting the continuous improvement of the Human Research Governance service.

About you

You will have: 

  • Relevant degree or equivalent experience, with a strong background in clinical research or project management.
  • Experience managing clinical studies across the full research lifecycle within NHS, academic or industry settings.
  • Excellent knowledge of clinical research regulations, governance and ethical frameworks.
  • Experience in study monitoring, data management and oversight of research sites.
  • Strong stakeholder management, communication and project management skills.
  • Excellent organisational skills with the ability to manage multiple priorities and deadlines.
  • A collaborative, proactive and adaptable approach to working across multidisciplinary teams.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it to the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

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