Clinical Trial Operation Manager

About the Role
This is an exciting opportunity to lead the delivery of a portfolio of cutting‑edge clinical trials, including CTIMPs and non‑CTIMPs, within a world‑leading translational research centre. The post holder will have both strategic oversight and hands‑on responsibility for trials across major international programmes, including 3TR, SQUEEZE, MDR‑RA, and AutoPiX.

A key element of the role is the management of multi‑country studies via the Clinical Trials Information System (CTIS), including regulatory submissions, lifecycle management, and coordination of approvals across EU Member States. You will work closely with the Barts Clinical Trials Unit to ensure compliance with UK and EU regulations and maintain high standards of governance and inspection readiness.

You will lead and coordinate the clinical research team at Mile End Hospital, overseeing study set‑up, recruitment, data quality, monitoring, and reporting. The role also involves identifying and managing risks, supporting continuous improvement, and contributing to strategic planning across the clinical portfolio.

Patient and Public Involvement and Engagement (PPIE) is integral to the role. You will help ensure patient perspectives are embedded in study design and delivery, supporting meaningful engagement and clear communication of research findings.

About You
Applicants should have substantial experience in clinical trial management, including CTIMPs, and a strong understanding of ICH‑GCP and UK regulatory frameworks. Leadership experience, excellent organizational skills, and the ability to work across multidisciplinary teams are essential.

About the School/Department/Institute/Project
Queen Mary University of London is seeking an experienced and motivated Clinical Trials Operations Manager to join the Centre for Experimental Medicine & Rheumatology (EMR), a world-leading research Centre specializing in precision medicine and biomarker‑driven clinical trials in autoimmune diseases. EMR brings together a multidisciplinary team of clinicians, scientists, and data experts to advance understanding of disease mechanisms and improve patient outcomes in conditions such as rheumatoid arthritis (RA), systemic lupus erythematosus, and Sjögren’s syndrome. The Centre is internationally recognized for its pioneering work in biopsy‑driven trials, including landmark studies published in The Lancet and Nature Medicine, and plays a key role within the Bart’s NIHR Biomedical Research Centre.

About Queen Mary
At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable.

Throughout our history, we’ve fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it’s simply ‘the right thing to do’ but for what it helps us achieve and the intellectual brilliance it delivers.

We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form.

Benefits
We offer competitive salaries, access to a generous pension scheme, 30 days’ leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities.

Queen Mary’s commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.

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