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Postdoctoral Research Associate

Imperial College London - Infection & Immunity, Genomic & Environment Medicine,National Heart and Lung Institute (NHLI)

Location: London
Salary: £38,566 to £47,579 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 22nd August 2019
Closes: 30th September 2019
Job Ref: MED01414

Location: St Mary’s Paddington 

Job Summary: 

We are seeking an enthusiastic and committed postdoctoral research associate to lead a programme of work to characterise the cellular immune responses in people recently exposed to TB. This work is part of the “Immune Mechanisms of Protection Against Mycobacterium tuberculosis (IMPAc-TB)” clinical study, a seven-year NIH-funded collaboration between Harvard University and the NIHR HPRU in Respiratory Infections/TB Research Centre at Imperial College London. You will collaborate locally and internationally with world leaders in TB research and apply cutting-edge techniques in systems immunology to cohorts of elite TB controllers. The overall aim is to identify common determinants of protection that can be translated into improved vaccine strategies.  

You will have previous experience in laboratory-based research along with strong organisational skills and the ability for rigorous and accurate documentation. You will have good interpersonal skills and be required to collaborate efficiently with members of the HPRU and other internal and external collaborators. 

You will join a dynamic team with a wide range of expertise in cellular immunology, molecular biology and bioinformatics to deliver on the objectives of the grant.

Duties and responsibilities

Alongside the project technician, you will perform high-dimensional flow cytometry on peripheral blood mononuclear cells (PBMC) and bronchoalveolar lavage (BAL) samples from elite TB controllers; define transcriptomic signatures and characterise humoral profiles by systems serology. You will be responsible for the integrity of samples, data and analysis in the project, as well as ensuring compliance with GCP, GDPR, MHRA guidelines and ethics. 

You will manage a small research team and work closely with research nurses locally and off-site and maintain relationships with international stakeholders and collaborators. 

Essential requirements 

You will have, or expect to submit soon, a PhD in Immunology or in a related discipline, with experience in working on clinical samples. You will ideally have experience in managing a multi-centre project with multiple stakeholders. 

You will be a conscientious team-player, supporting other scientists and students in the lab, providing training and support where necessary and contributing to the upkeep of the laboratory. You will be expected to participate in discussions of the wider work of the HPRU. 

Further information 

The post is full-time and fixed-term for 3 years. 

Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £35,477- £38,566 per annum.

Informal enquiries should be directed to Dr Rhia Kundu   

For technical issues when applying online please email 

Committed to equality and valuing diversity, we are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and are working in partnership with GIRES to promote respect for trans people.

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