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Laboratory Technician - Membrane Protein and Nanobody Production

University of Oxford - Nuffield Department of Medicine, Structural Genomics Consortium

Location: Oxford
Salary: £22,417 to £25,941 p.a. Grade 4
Hours: Full Time, Part Time
Contract Type: Fixed-Term/Contract
Placed On: 8th November 2019
Closes: 20th November 2019
Job Ref: 143944

Nuffield Department of Medicine, Structural Genomics Consortium, Old Road Campus Research Building, Old Road Campus, Roosevelt Drive, Headington, Oxford

At the SGC we study proteins involved in cancer, metabolic disease and neuropsychiatric disorders, to promote the development of new drugs for these severe diseases. We are seeking a Laboratory Technician to assist Liz Carpenter’s Integral Membrane Proteins (IMPs) group with production of human IMPs and key tool proteins, antibodies and nanobodies, which are essential for structural and functional studies of the IMPs.

You would assist with culturing insect and mammalian cells as starting materials for purifications. You would help with identifying the right conditions for making proteins, then assist with producing the proteins. These protein samples will be used to generate a series of antibodies and nanobodies, which you will help to purify and characterise. These essential tools will be used for structural biology, and to understand the function and role of the proteins in cells. You would also be involved with equipment maintenance, stock keeping and placing orders.

You will be joining a team of 12 highly motivated and enthusiastic membrane protein scientists, who work closely together to achieve their objectives. As you would be working in a challenging area, you must be keen to acquire new technical skills. You would be working with many members of the IMP group and other scientists in the SGC, so excellent interpersonal and communication skills are essential.

To be suitable for this post you will have demonstrable experience in academic or industrial laboratories in protein purification and molecular biology, including the use of purification systems. You will have good computer skills, be organised, precise and reliable in both performance and reporting. You will have knowledge of health and safety regulations, the ability to work as part of a team and to be able to communicate/collaborate with colleagues verbally and in writing.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application.

This post is full-time (we would also consider part-time) on a fixed-term contract until 31 August 2022 in the first instance and is funded by Innovative Medicines Initiative and BBSRC.

Please quote reference 143944 on all correspondence.

Only applications received before 12.00 noon on 20 November 2019 will be considered.

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