Back to search results

Project Research Scientist (Bioinformatician)

The Francis Crick Institute

Location: London
Salary: £45,000
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 15th October 2021
Closes: 30th November 2021
Job Ref: R464
 

Contract: Fixed Term (until May 2023), Full time

Salary: Circa £45,000

Short summary

Altered metabolism is one of the cancer hallmarks and offers promising opportunities for designing new therapies. We are using mouse models and metabolomics approaches to evaluate the requirement of metabolic pathways for tumours carrying specific genetic lesions. The complexity of metabolic interactions between a tumour and the rest of the body, flexibility of metabolism and inter and intra tumour heterogeneity present challenges that require the development of new approaches in order to understand how to target the altered metabolism of tumours efficiently and specifically.

Our lab uses various metabolomics approaches to evaluate the activity of metabolic pathways in vivo including mass spectrometry imaging. Ultimately we are aiming to determine how metabolic changes are aligned with genetic profiles of tumours in time and space and how these interactions determine tumours’ metabolic vulnerabilities. The post holder will be a part of the team of researchers in Mariia Yuneva’s lab and will also interact with researchers from National Physical Laboratory and Imperial college London.

The successful candidate is likely to be an energetic, focused, and productive individual with a desire to work in a congenial, dynamic, and collaborative research environment. Good organisational, analytical, and communication skills are essential.

Project scope

Specific objectives will include, but not be limited to:

  • Perform metabolomics analysis of tissue samples, including sample preparation and data analysis.
  • Design experiments in collaboration with wet-lab scientists and integrate experimental data including transcriptomics, proteomics, metabolomics (including stable isotope based in vitro and in vivo metabolomics) and mass spectrometry imaging.
  • Regularly attend and participate in scientific meetings in Mariia Yuneva’s lab, several larger interest groups and forums at the Crick as well as with collaborators.
  • Write and contribute to the preparation of scientific manuscripts, reports, presentations and records of experimental plans and results
  • Supervise and provide technical advice to other team members when appropriate

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy. 

  • If you are interested in applying for this role, please apply via our website.
  • The closing date for applications is 30th November 2021.
  • All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.
We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from The Francis Crick Institute

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge